PreveCeutical Medical Inc.

lockPrivate Group

Headquartered in Vancouver, British Columbia, PreveCeutical Medical Inc. has a world class team with a passion for researching and developing innovative solutions for unmet clinical needs. Bringing to market treatments and therapies that make real, palpable differences in the lives of those who n...

people7 Members       (0)

Corporate Profile
Group Admins:
  • Thumb 8020 monitor 200 200  png
  • Thumb no photo
Request Membership


PreveCeutical Medical Inc.

lockPrivateGroup

Headquartered in Vancouver, British Columbia, PreveCeutical Medical Inc. has a world class team with a passion for re......

people7 Members       (0)

Thumb 8020 monitor 200 200  png

8020 Admin

13 hours

8020 Admin posted a press release PreveCeutical Granted Approval to Acquire and Use Human Mucosal Tissue for Final Phase of Sol-Gel Program in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - May 21, 2019) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), announces that the Company's research team at the University of Queensland has been granted the necessary approvals from a local hospital's Human Ethics Committee to acquire and use human nasal mucosal tissue (mucosal membrane) for the final phase of the cannabinoid-based, soluble gel ("Sol-gel") drug delivery research and development program (the "Sol-gel Program").


For this final phase of the Sol-gel Program, PreveCeutical intends to study and report on the delivery of the cannabis-infused Sol-gels to freshly explanted nasal mucosal tissue. PreveCeutical has previously demonstrated, using an adult human nasal cast, that the Company's cannabinoid-based Sol-gel is delivered to and retained directly at target tissue high in the nasal cavity when administered with a custom Sol-gel applicator device (the "Sol-gel Applicator") (see news release dated November 19, 2018).


PreveCeutical's President and Chief Science Officer, Dr. Mak Jawadekar stated, "Getting approval to acquire and use human mucosal tissue for this final phase of the Sol-Gel program allows us work on a proof of concept for Sol-Gel delivery in a laboratory setting."


PreveCeutical believes that the outcomes of its Sol-gel Program may be of value to companies interested in delivering cannabinoid/cannabis-based-derived pharmaceuticals to the central nervous system (the "CNS"). Achieving patient benefit from the use of medicinal cannabis for the management of CNS conditions, such as epilepsy, anxiety and depression, may be a function of achieving effective and sustained delivery of the cannabis-based therapeutic to brain tissue. When taken orally, medicinal cannabis can cause gastrointestinal upset, before being absorbed across the gut into the blood stream, where it is rapidly metabolised, and has the potential to interact with other medicines a patient may be taking. As common drug delivery methods do not provide effective and sustained delivery to the brain, the delivery of cannabinoids directly to the CNS remains a significant challenge.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilising organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the Sol-gel Program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Dr. Makarand (Mak) Jawadekar"
President& Chief Science Officer


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include any statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the ability of the Company to acquire human nasal mucosal tissue in quantities necessary to complete the final phase of the Sol-gel Program, and the Company's anticipated business plans and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "will", "pro forma", "plans", "expects", "may", "should", "budget", "schedules", "estimates", "forecasts", "intends", "anticipates", "believes", "potential", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Actual results could differ from those projected in any forward-looking statements due to numerous factors including risks and uncertainties relating to the risks associated with the completion of Sol-gel Program, actual results from tests using human nasal mucosal tissue and from clinical trials, dependence on collaborative partners and the prospects for negotiating additional corporate collaborations or licensing arrangements and their timing, the inability of the Company, to, among other things, protect its intellectual property, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialize any therapeutics from the Company's research programs, pursue business partnerships, complete its research programs as planned, and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the biotechnology or pharmaceutical industry, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.



To view the source version of this press release, please visit https://www.newsfilecorp.com/release/44909

!
Thumb 8020 monitor 200 200  png

8020 Admin

1 month

8020 Admin posted a press release PreveCeutical Partnership Leads to Two New Patent Filings in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - April 17, 2019) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical") announces that the Company's research collaboration with UniQuest and The University of Queensland ("UQ") has led to the filing of two new patent applications for cyclic peptides and their use in pain management (the "Patent Applications").


The Patent Applications follow from PreveCeutical entering into a research agreement in 2018 (see news release dated January 30, 2018) with UniQuest, UQ's commercialisation company. The research includes the application of UQ's disulphide linker technology to potentially develop non-addictive analgesics (the "Analgesics Research Program").


The two new Australian Patent Office patent files are:



  1. Australian Patent Application No. AU2019/900226, entitled "A Cyclic Peptide" filed January 24, 2019; and,

  2. Australian Patent Application No. AU2019/900292, entitled "A Cyclic Peptide" filed January 30, 2019.


PreveCeutical's President and Chief Science Officer, Dr. Mak Jawadekar stated: "I am pleased by the two new Australian patent applications which are based upon PreveCeutical's research collaboration with UQ and UniQuest. We are incredibly excited by our partnership with UniQuest and the intellectual property arising from the non-addictive analgesics program at UQ. The research program aims to develop a non-addictive alternative to opioid painkillers by developing cyclic peptides. Opioid-based pain treatments such as morphine, codeine and fentanyl activate the mu opioid receptor, which can be highly addictive. This research provides a potential mechanism for pain treatment without activating that receptor. An additional potential advantage of the cyclic peptides is their enhanced metabolic stability and more importantly oral bioavailability, meaning that they could be taken orally rather than intravenously."


UQ School of Pharmacy researchers, Associate Professor Peter Cabot and Dr. Harendra (Harry) Parekh are leading the two-year research program into the peptides and their potential application as a treatment for pain.


UniQuest CEO, Dr. Dean Moss stated: "The patent applications represent an important milestone in our relationship with PreveCeutical and follow the entry into three other research agreements with PreveCeutical in recent years, including an agreement to stabilise peptides isolated from scorpion venom for use in immune-boosting applications; an agreement for the development of a new formulation to deliver cannabinoids directly to the central nervous system via the nasal cavity; and an agreement for a gene therapy to treat diabetes and obesity."


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilising organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the soluble gel drug delivery research and development program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


About UniQuest


UniQuest is Australia's leading commercialisation entity, specialising in commercialising the intellectual property of The University of Queensland, a global top 50 university. UniQuest benchmarks in the top tier of technology transfer worldwide.


For more information about UniQuest, please visit https://uniquest.com.au/.


On Behalf of the Board of Directors of PreveCeutical


"Dr. Makarand (Mak) Jawadekar"
President & Chief Science Officer


For further information, please contact


PreveCeutical:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include any statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the granting of the Patent Applications and the continued research interests of PreveCeutical, PreveCeutical anticipated business plans and their prospects of success in executing their proposed plans. Often, but not always, forward-looking statements can be identified by words such as "will", "pro forma", "plans", "expects", "may", "should", "budget", "schedules", "estimates", "forecasts", "intends", "anticipates", "believes", "potential", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Forward looking statements are based on certain assumptions regarding PreveCeutical, including expected growth, results of operations, including PreveCeutical's research and development activities, performance, industry trends, growth opportunities, and that PreveCeutical will be able to obtain the financing required to carry out its planned future activities, retain and attract qualified research personnel and obtain and/or maintain the necessary intellectual property rights needed to carry out future business activities.


Actual results could differ from those projected in any forward-looking statements due to numerous factors including, risks and uncertainties relating to: complexities and delays in connection with research and development activities and the actual results of research and development activities including the Analgesics Research Program; the acceptance of the Patent Appplications and the granting of the patents thereunder; the ability of PreveCeutical, to, among other things, protect their respective intellectual property, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities; and the ability of PreveCeutical to commercialise the Analgesics Research Program, pursue business partnerships, complete their research programs as planned, and obtain the financing required to carry out their planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the biotechnology or pharmaceutical industry, may also adversely affect the future results or performance of PreveCeutical. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, PreveCeutical assume no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although PreveCeutical believe that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by PreveCeutical from time-to-time. These reports and PreveCeutical's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.


To view the source version of this press release, please visit https://www.newsfilecorp.com/release/44147

!
Thumb 8020 monitor 200 200  png

8020 Admin

1 month

8020 Admin posted a press release PreveCeutical Files Application to Human Ethics Committee to Acquire Human Tissue for the Final Phase of the Sol-Gel Program in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - April 15, 2019) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), announces the Company's research team at the University of Queensland has filed an application to a local hospital's Human Ethics Committee (the "Human Ethics Committee") to acquire human nasal mucosal tissue (mucosal membrane) for use in the final phase of the cannabinoid-based, soluble gel ("Sol-gel") drug delivery research and development program (the "Sol-gel Program").


PreveCeutical has previously demonstrated effective delivery and retention of the Sol-gels to the olfactory epithelium in an adult human nasal cast using a custom applicator device (the "Sol-gel Applicator") (see news release dated November 19, 2018).


PreveCeutical's President and Chief Science Officer, Dr. Mak Jawadekar stated: "This is an important next step for the Sol-gel Program. Having demonstrated, in an in-vitro model, using an adult human nasal cast, that the Company's CBD Sol-gel is delivered to and retained directly at target tissue high in the nasal cavity when administered with the Sol-gel Applicator, we look forward to testing the Sol-gels on human nasal tissue. This will allow PreveCeutical to potentially deliver a host of therapeutics safely from nose-to-brain in a reliable and sustained manner, which remains a significant challenge for many companies, globally."


PreveCeutical believes that the outcomes of its Sol-gel Program may be of value to companies interested in delivering pharmaceuticals to the central nervous system (the "CNS"). Achieving patient benefit from the use of medicinal cannabis for the management of CNS conditions, such as epilepsy, anxiety and depression, may be a function of achieving effective and sustained delivery of the cannabis-based therapeutic to brain tissue. When taken orally, medicinal cannabis can cause gastrointestinal upset, and when absorbed across the gut it is broken down by enzymes. As common drug delivery methods do not provide effective and sustained delivery to the brain, the delivery of cannabinoids to the CNS is a universal problem.


Should the application to the Human Ethics Committee be granted, the final phase of the Sol-gel Program may begin. During the final phase, the Company intends to study and report on the delivery of the cannabis-infused Sol-gels to freshly explanted nasal mucosal tissue.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilising organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the Sol-gel Program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Dr. Makarand (Mak) Jawadekar"
President& Chief Science Officer


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include any statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the ability of the Company to have its application to acquire human nasal mucosal tissue by the Human Ethics Committee approved, and if approved, to acquire human nasal mucosal tissue, and the Company's anticipated business plans and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "will", "pro forma", "plans", "expects", "may", "should", "budget", "schedules", "estimates", "forecasts", "intends", "anticipates", "believes", "potential", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Actual results could differ from those projected in any forward-looking statements due to numerous factors including risks and uncertainties relating to the risks associated with the completion of Sol-gel Program, actual results from clinical trials, dependence on collaborative partners and the prospects for negotiating additional corporate collaborations or licensing arrangements and their timing, the inability of the Company, to, among other things, protect its intellectual property, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialise any therapeutics from the Company's research programs, pursue business partnerships, complete its research programs as planned, and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the biotechnology or pharmaceutical industry, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.


To view the source version of this press release, please visit https://www.newsfilecorp.com/release/44078

!
Thumb 8020 monitor 200 200  png

8020 Admin

1 month

8020 Admin posted a press release PreveCeutical Announces Further Results from its Preliminary Screening of Peptides Derived from Blue Scorpion Venom in a Cell-Based Brain Cancer Model in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - April 10, 2019) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), is pleased to announce further positive results from the preliminary screening of key peptides from its scorpion venom-derived peptide research and development program (the "Peptide Program"), that is expected to enable the Company to generate Nature Identical™ peptide therapeutics intended for therapeutic applications. PreveCeutical's initial focus is to understand the activities of such peptides in cell-based brain cancer models.


Through preliminary screening in a glioblastoma (aggressive brain cancer) cell-based assay, PreveCeutical's research team has successfully identified four lead peptides that inhibit the activity of a target protein (the "Target Protein") implicit in the progression of certain glioblastomas (see news release dated March 11, 2019).


After further screening of the lead peptides in an invasion assay model, PreveCeutical is pleased to announce that the peptides' abilities to inhibit the activity of the Target Protein and the invasion potential by glioblastoma cell types has been confirmed. This is an important development given that "invasion" is a key driver of the aggressiveness, the poor prognosis and the rapid spread of glioblastoma.


Although this screening process is nearing completion, the Peptide Program is ongoing. This latest encouraging development has helped progress the Company towards assessing the efficacy of the lead peptides in more sophisticated neural oncosphere cell models of glioblastoma. The results from such additional screening will be helpful in determining further applications of research generated from the Peptide Program.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the soluble gel drug delivery program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Dr. Makarand Jawadekar"
President & Chief Science Officer


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include any statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the ability of the Company to generate Nature Identical™ peptide therapeutics for therapeutic applications, to develop a more detailed understanding of the activities of the peptides and assess the efficacy of the peptides in more sophisticated neural oncosphere cell models and the Company's anticipated business plans and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "will", "pro forma", "plans", "expects", "may", "should", "budget", "schedules", "estimates", "forecasts", "intends", "anticipates", "believes", "potential", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Actual results could differ from those projected in any forward-looking statements due to numerous factors including risks and uncertainties relating to the risks associated with the completion of Peptide Program, actual results from clinical trials, dependence on collaborative partners and the prospects for negotiating additional corporate collaborations or licensing arrangements and their timing, the inability of the Company, to, among other things, protect its intellectual property, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialise any therapeutics from the Company's research programs, pursue business partnerships, complete its research programs as planned, and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the biotechnology or pharmaceutical industry, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!
Thumb 8020 monitor 200 200  png

8020 Admin

2 months

8020 Admin posted a press release IIROC Trade Resumption - PREV in PreveCeutical Medical Inc.





Company:  PreveCeutical Medical Inc.


CSE Symbol: PREV (all issues)


Resumption (ET): 9:30 AM


IIROC can make a decision to impose a temporary suspension (halt) of trading in a security of a publicly-listed company. Trading halts are implemented to ensure a fair and orderly market. IIROC is the national self-regulatory organization which oversees all investment dealers and trading activity on debt and equity marketplaces in Canada.


SOURCE Investment Industry Regulatory Organization of Canada (IIROC)


View original content: http://www.newswire.ca/en/releases/archive/April2019/05/c8855.html

For further information about IIROC's trading halt policy, please see Trading Halts & Timely Disclosure (http://www.iiroc.ca/industry/marketmonitoringanalysis/Pages/Trading-Halts-Timely-Disclosure.aspx) at www.iiroc.ca under the Halts & Resumptions tab. Please note that IIROC staff cannot provide any information about a specific halt beyond what is contained in this halt notice. For general information about IIROC, contact IIROC's Complaints & Inquiries team at inquiries@iiroc.ca or 1-877-442-4322 (Option 2). For company-related enquiries, contact the company directly

!
Thumb 8020 monitor 200 200  png

8020 Admin

2 months

8020 Admin posted a press release Retraction to News Release dated April 4, 2019 in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - April 4, 2019) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), announces that, at the request of the Investment Industry Regulatory Organization of Canada, it hereby retracts certain statements regarding estimated annual production, valuation and harvest quantities from the Toowoomba Medicinal Cannabis Project contained in its news release dated April 4, 2019. The presentation of this information is not consistent with requirements for the disclosure of forward looking information.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the Sol-gel drug delivery program; Nature Identical™ peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


For further information, please contact:


PREVECEUTICAL MEDICAL INC.
Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


To view the source version of this press release, please visit https://www.newsfilecorp.com/release/43898

!
Thumb 8020 monitor 200 200  png

8020 Admin

2 months

8020 Admin posted a press release IIROC Trading Halt - PREV in PreveCeutical Medical Inc.


VANCOUVER, April 4, 2019 /CNW/ - The following issues have been halted by IIROC:


Company: PreveCeutical Medical Inc.


CSE Symbol: PREV (all Issues)


Reason: Pending Company Contact


Halt Time (ET): 15:07


IIROC can make a decision to impose a temporary suspension (halt) of trading in a security of a publicly-listed company. Trading halts are implemented to ensure a fair and orderly market. IIROC is the national self-regulatory organization which oversees all investment dealers and trading activity on debt and equity marketplaces in Canada.


SOURCE Investment Industry Regulatory Organization of Canada (IIROC) - Halts/Resumptions


View original content: http://www.newswire.ca/en/releases/archive/April2019/04/c2091.html



For further information about IIROC's trading halt policy, please see Trading Halts & Timely Disclosure (http://www.iiroc.ca/industry/marketmonitoringanalysis/Pages/Trading-Halts-Timely-Disclosure.aspx) at www.iiroc.ca under the Halts & Resumptions tab. Please note that IIROC staff cannot provide any information about a specific halt beyond what is contained in this halt notice. For general information about IIROC, contact IIROC's Complaints & Inquiries team at inquiries@iiroc.ca or 1-877-442-4322 (Option 2). For company-related enquiries, contact the company directly.Copyright CNW Group 2019

!
Thumb 8020 monitor 200 200  png

8020 Admin

2 months

8020 Admin posted a press release Asterion Welcomes Australian Government Awarding of Major Project Status for its Toowoomba Medicinal Cannabis Project in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - April 4, 2019) - Asterion Cannabis Inc. (P.ASTR) ("Asterion") and PreveCeutical Medical Inc. ("PreveCeutical") (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H), announce today that Asterion's wholly-owned Australian subsidiary, Asterion Australia Pty Ltd, has been awarded Major Project Status for Asterion's Toowoomba Medicinal Cannabis Project (the "Toowoomba Project" or the "Facility") by the Australia Federal Government.


Asterion's CEO, Stephen Van Deventer, welcomed the announcement by the Australian Federal Industry, Innovation and Science Minister, Hon Karen Andrews MP, and stated, "Asterion chose Australia to develop the world's largest medicinal cannabis glasshouse because of the Australian Government's ambition to become the world's largest exporter of cannabis products for medicinal purposes, as announced by the Australian Federal Health Minister Hon Greg Hunt MP in January 2018." Mr. Van Deventer continued, "Asterion looks forward to working with the Federal and Queensland Governments and the Toowoomba Council throughout the development process, to deliver the largest and most technically advanced glasshouse in the world to the south eastern Queensland community and to deliver the finest quality in medical cannabis products to patients."

 

Major Project Status recognises the strategic significance of the Toowoomba Project to Australia, and provides coordination and facilitation support as well as a single-entry point to a coordinated approvals process. In order for the Toowoomba Project to have been considered for Major Project Status, it had to meet the Major Project Status requirements, including an estimated investment of AUD $50 million or more, strategic significance to Australia and certain Australian government approvals. The project proponent must also have the financial resources to complete the approvals process and the project must have reasonable commercial viability.

 

Toowoomba Project

 

The Toowoomba Project will be located on 75 hectares in Toowoomba adjacent to the Wellcamp Airport. The Facility is expected to be built to European Union Good Manufacturing Practices for medicinal products (EU-GMP) standards and, when complete, is planned to include a 40 hectare (4.3 million square feet) state-of-the-art glasshouse for cultivation and processing, in addition to a research centre and manufacturing facility, including administration and staff facilities. The Toowoomba Project is expected to be among the largest glasshouse facilities globally. The Facility is also expected to have the most advanced glasshouse cultivation technologies, including AI and robotics, and set new benchmarks in productivity, control, product quality and consistency. The Facility is anticipated to employ a state of the art security systems and implement best practice procedures to ensure the physical security of production and shipping, as well as traceability of products after shipment.

 

A three-stage establishment plan for the Toowoomba Project is expected to be implemented commencing in the last quarter of 2019, with a total capital cost in the approximate amount of $450 million. A total daily direct workforce of an estimated 800 workers will be employed with an additional 300 part time and shift-based positions. These positions range from semi-skilled workers through to scientists undertaking advanced research in both medicines and horticulture.

 

It is estimated that annual production from the Facility will be approximately 500,000 kg of medicinal cannabis product, having an export value in excess of $1 billion, with approximately 20,000 plants harvested per day.

 

Research and Development

 

Clonal propagation research conducted at the Facility will be funded by Asterion and undertaken by Queensland University Queensland Alliance for Agriculture and Food Innovation (QAAFI) (www.qaafi.uq.edu.au), with the plan to develop an in vitro mass propagation protocol for selected cultivars of Asterion's elected cannabis strains.

 

Asterion is working with PreveCeutical and UniQuest Pty Limited on the development of new medical applications for cannabis in both preventative and treatment applications. In addition, under its September 26, 2018 development and joint venture agreement with Asterion, PreveCeutical will make available to Asterion its soluble gel (Sol-gel) delivery system (the "Sol-Gel System"). Sol-gels are taken via nasal administration and rapidly gel upon contact with mucosal tissue, which paves the way for direct nose-to-brain delivery. PreveCeutical is currently developing its Sol-Gel System, with the goal of developing the first, sustained-release, cannabis and CBD-based Sol-gel nose-to-brain delivery system that will provide relief across a range of indications from pain, inflammation, seizures, and neurological disorders.

 

About Asterion

 

Asterion is a Canadian cannabis company with operations in Australia, specializing in organic medical cannabis with a goal of becoming an industry leader in next generation cannabis products. The company is focused on the future of precision agriculture and aims to produce the highest quality genetically uniform cannabis strains, at an affordable price.

 

Asterion is led by a team of highly experienced executives with over 120 years of combined experience in medical cannabis, renewable energy, capital markets, and other highly relevant sectors across North America, Oceania, Europe, Africa and Asia.

 

About PreveCeutical

 

PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.

 

PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the Sol-gel drug delivery program; Nature Identical™ peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).

 

On Behalf of the Board of Directors of PreveCeutical

 

"Dr. Mak Jawadekar"

President and Chief Science Officer

 

On Behalf of the Board of Directors of Asterion

 

"Stephen Van Deventer"

Chief Executive Officer

 

For further information, please contact:

 

Preveceutical Medical Inc.

Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com

Asterion:

Investor Relations
info@asterioncannabis.com


 


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the construction of the Facility and the implementation date and capital costs in connection therewith, the development functionality, productivity, production capacity and features of the Facility and the efficacy, consistency and quality of the cannabis products produced at the Facility, including the products used in PreveCeuitcal's Sol-gel System, the outcome and success of the Toowoomba Project and the Sol-gel System, the workforce requirements to operate the Facility, matters related to Asterion and PreveCeutical's current and planned projects and programs, including the Toowoomba Project and the Sol-gel program, and Asterion and PreveCeutical's anticipated business plans and prospect of success in executing each of their plans. Often, but not always, forward-looking statements can be identified by words such as "will", "plans", "expects", "may", "intends", "anticipates", "believes", "proposes", "estimates" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Actual results could differ from those projected in any forward-looking statements due to numerous factors including, but not limited to, the inability of Asterion and PreveCeutical to, among other things, successfully carry out the Toowoomba Project and construct the Facility and obtain the required regulatory approvals and financing required for same, execute their proposed business plans and obtain the financing required to carry out planned future activities. Other factors such as general economic, market or business conditions, future prices of cannabis, changes in the financial markets and in the demand and market price for cannabis, or changes in laws, regulations and policies affecting the biotechnology or medical cannabis industry and delays in obtaining governmental and regulatory approvals, including for the Toowoomba Project and the Sol-gel program, may also adversely affect the future results or performance of Asterion and PreveCeutical. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, neither Asterion nor PreveCeutical assumes any obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although Asterion and PreveCeutical believe that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by Asterion and PreveCeutical from time-to-time.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.


To view the source version of this press release, please visit https://www.newsfilecorp.com/release/43892

!
Thumb 8020 monitor 200 200  png

8020 Admin

2 months

8020 Admin posted a press release PreveCeutical Announces Preliminary Screening Results of Peptides Derived From Blue Scorpion Venom in a Cell-Based Brain Cancer Model in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - March 11, 2019) -  PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), is pleased to announce positive results from the preliminary screening of key peptides from its scorpion venom-derived peptide research and development program (the "Peptide Program"), that is expected to enable the Company to generate Nature Identical™ peptide therapeutics intended for therapeutic applications. PreveCeutical's initial focus is to understand the activities of such peptides in cell-based brain cancer models.


Through preliminary screening in a glioblastoma cell-based assay, PreveCeutical's research team has successfully identified four lead peptides that inhibit the activity of a target protein implicit in the progression of certain aggressive brain cancers.


Further, the re-designed and synthesised peptides were found to be equally or more potent in the cell-based activity assay when compared to another scorpion peptide, Chlorotoxin. A series of more comprehensive screening assays are underway in the final stage of the Peptide Program, to allow the Company to develop a more detailed understanding of the activities of the peptides in progressively complex cell-based brain cancer models. No clinical studies have been planned to be undertaken at this time.


PreveCeutical's President, Dr. Mak Jawadekar, commented, "This is a key milestone for PreveCeutical, as this research program underway in Queensland, Australia has successfully identified four lead peptides from blue scorpion venom."


Dr. Harry Parekh, PreveCeutical's Chief Research Officer commented, "We have identified novel, lead peptide candidates that inhibit activity of a key protein implicated in driving the aggressive nature of certain brain cancers. From a practical perspective, these lead peptides are attractive as they are a fraction of the size and complexity of an earlier reported scorpion-derived peptide, Chlorotoxin."


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the soluble gel drug delivery program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9® is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on the Company's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Stephen Van Deventer"
Chairman and CEO


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include any statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the ability of the Company to generate Nature Identical™ peptide therapeutics for therapeutic applications, to develop a more detailed understanding of the activities of the peptides in complex cell-based brain cancer models and the Company's anticipated business plans and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "will", "pro forma", "plans", "expects", "may", "should", "budget", "schedules", "estimates", "forecasts", "intends", "anticipates", "believes", "potential", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Actual results could differ from those projected in any forward-looking statements due to numerous factors including risks and uncertainties relating to the inability of the Company, to, among other things, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialise any therapeutics from the Company's research programs, pursue business partnerships, complete its research programs as planned, and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the biotechnology or pharmaceutical industry, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.


To view the source version of this press release, please visit https://www.newsfilecorp.com/release/43322

!
Thumb 8020 monitor 200 200  png

8020 Admin

4 months

8020 Admin posted a press release PreveCeutical to Explore Partnerships with Pharmaceutical and Biotechnology Companies for the Co-Development of its Sol-Gel System in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - January 29, 2019) - PreveCeutical Medical Inc. (the "Company" or "PreveCeutical") (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H), announces that it plans to commence exploratory discussions with pharmaceutical and biotechnology companies developing therapies for neurological disorders, that are seeking a targeted nose-to-brain drug delivery system in connection with same, with the intention of forming a partnership for the co-development of the Company's soluble gel ("Sol-gel") system.


The Company has previously demonstrated effective delivery and retention of its Sol-gels to the olfactory epithelium in an adult human nasal cast using its custom applicator device (the "Sol-gel Applicator") (see news release dated November 19, 2018). PreveCeutical now believes that this system may be of value to companies interested in delivering pharmaceuticals to the central nervous system (CNS).


PreveCeutical believes that the pharmaceutical industry faces significant challenges in delivering drugs to the brain, and that this can be a major obstacle in successfully developing effective treatments for neurological disorders. Starting a dialogue with potential partners will assist PreveCeutical in gauging the potential value of its nose-to-brain delivery approach, and in assessing whether partnership opportunities exist.


PreveCeutical's Chief Science Officer, Dr. Mak Jawadekar, will be responsible for leading discussions with external partners for the co-development of this system. Dr. Jawadekar has 28 years of experience working at Pfizer Inc. For many of these years he was involved in external Drug Delivery Technology Assessment function involving novel applicable technologies, which are patent protected. Further, he has extensive experience in creating and cultivating external partnerships and alliances for such technologies. Dr. Jawadekar began his professional career at Pfizer Central Research in early 1982, after having completed his Ph.D. in Pharmaceutics at the University of Minnesota.


"Sol-gel technology has certainly shown significant promise in laboratory testing at this point. Eventually, I would like to see this proprietary technology be successfully applied to a drug which could be targeted for CNS delivery. At the right time, we would welcome an opportunity to work with a pharmaceutical or biotechnology company to co-develop the Sol-gel and Sol-gel Applicator to be used in pharmaceutical and therapeutic products," stated PreveCeutical's Chief Science Officer, Dr. Mak Jawadekar.


"I am quite excited about this initiative. PreveCeutical started to work on the Sol-gel program over 22 months ago. By now, achieving primary proof of concept (POC) goals are on target to be met and preliminary results observed to date seem to exceed our expectations. PreveCeutical looks forward to opening new doors to work on co-developing the Sol-gel platform. Under the direction of Dr. Jawadekar, I am extremely confident of the possibilities," said PreveCeutical's Chairman, CEO and President, Stephen Van Deventer.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilising organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the Sol-gel Program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9 is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on the Company's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Stephen Van Deventer"
Chairman, CEO and President


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the commencement of exploratory discussions, and the entry into of a partnership, with one or more pharmaceutical and biotechnology companies for the co-development of the Company's Sol-gel system, the development and testing of the Sol-gel formulations and the Sol-gel Applicator, the efficacy of the Company's products, matters related to the Company's current and planned research and development programs, including the Sol-gel drug delivery research and development program, the Company's anticipated business plans and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "plans", "expects", "may", "intends", "anticipates", "believes", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Actual results could differ from those projected in any forward-looking statements due to numerous factors including, risks and uncertainties relating to the inability of the Company, to, among other things, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialise therapeutic and diagnostic technologies, execute its proposed business plans, pursue business partnerships including, but not limited to, a partnership with a pharmaceutical and biotechnology company for the co-development of the Company's Sol-gel system, complete its research programs as planned and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the biotechnology, pharmaceutical or cannabis industries, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.



To view the source version of this press release, please visit https://www.newsfilecorp.com/release/42513

!
Thumb 8020 monitor 200 200  png

8020 Admin

4 months

8020 Admin posted a press release PreveCeutical Provides Update on Research Program for Development of Non-Addictive Analgesics in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - January 8, 2019) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical") is pleased to announce that it has recently completed a systematic and comprehensive series of in silico guided design, synthesis and potency screening of a library of carefully designed peptide constructs intended for development as non-addictive analgesics.


Through this meticulous process we have identified no less than five novel peptide constructs, which preferentially target the receptor subtype which is of interest to the Company and is purported to avoid addictive and tolerance-inducing side effects.


Furthermore, we confirm that this novel subset of peptides has demonstrated potency, in a well-accepted functional dose response assay, that is on par with clinically available agents, such as morphine.


PreveCeutical's peptide research program, led by the Company's Chief Research Officer, Dr. Harendra Parekh, is expected to further elaborate on this promising series of peptides, with the goal of employing design strategies that include a proprietary linker technology to enhance the analgesic peptides' stability, while maintaining their exceptional potency.


Dr. Parekh commented, "We are very pleased with this promising development, as a result of numerous iterations between our peptide design and cell-based screening efforts, we have now yielded a number of constructs which discriminate between the key pain receptors in the body, and importantly, avoid activation of those purported to lead to dependence."


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for type 2 diabetes and obesity; a soluble gel drug delivery program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9® is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on the Company's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Stephen Van Deventer"
Chairman, CEO and President


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, matters related to the Company's current and planned research and development programs, including the non-addictive analgesic peptides as a replacement to the highly addictive analgesics, such as morphine, the Company's anticipated business plans and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "plans", "expects", "may", "intends", "anticipates", "believes", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Forward looking statements are based on certain assumptions regarding the Company, including expected growth, results of operations, including the Company's research and development activities, performance, industry trends, growth opportunities, and that the Company will be able to obtain the financing required to carry out its planned future activities, retain and attract qualified research personnel and obtain and/or maintain the necessary intellectual property rights it needs to carry out its future business activities. Actual results could also differ from those projected in any forward-looking statements due to numerous factors including, risks and uncertainties relating to complexities and delays in connection with research and development activities and the actual results of research and development activities, and the inability of the Company, to, among other things, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialise therapeutic and diagnostic technologies, execute its proposed business plans, pursue business partnerships, complete its research and product development programs as planned and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the healthcare and cannabis industries in Canada may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, intentions and assumptions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations intentions or assumptions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!
Thumb 8020 monitor 200 200  png

8020 Admin

4 months

8020 Admin posted a press release PreveCeutical Files Notice of Civil Claim Against the BridgeMark Group in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - January 7, 2019) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), announces that on December 17, 2018 it filed a Notice of Civil Claim with the Supreme Court of British Columbia (the "Notice of Civil Claim") against Aly Babu Mawji, Justin Liu, BridgeMark Financial Corp., Rockshore Advisors Ltd. (formerly known as, Cam Paddock Enterprises Inc.), Detona Capital Corp., Escher Invest SA, Essos Corporate Services Inc., Jarman Capital Inc., JCN Capital Corp., Kendl Capital Limited, Lukor Capital, Northwest Marketing and Management Inc., Sway Capital Corp. and Tryton Financial Corp. (collectively, the "BridgeMark Group").


In the Notice of Civil Claim, PreveCeutical made claims against the BridgeMark Group for fraudulent misrepresentation, breach of contract, conspiracy, unjust enrichment and breach of duty of honest performance in connection with services that the BridgeMark Group failed to provide to PreveCeutical, and various consulting agreements (the "Consulting Agreements") and subscription agreements (the "Subscription Agreements") entered into between PreveCeutical and certain members of the BridgeMark Group


The relief sought by PreveCeutical in the Notice of Civil Claim includes: rescission of the Consulting Agreements and the Subscription Agreements; all necessary actions to effect such recession, including an order that the relevant members of the BridgeMark Group return the securities issued to them by PreveCeutical under the Subscription Agreements and refund the consulting fees paid to them by PreveCeutical under the Consulting Agreements; damages; costs; and pre and post judgement interest.


"Given the conduct of the BridgeMark Group, we have no other choice but to defend the interests of our shareholders by pursuing this Notice of Civil Claim," said PreveCeutical's Chairman, CEO and President, Stephen Van Deventer.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for type 2 diabetes and obesity; a soluble gel drug delivery program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9® is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on the Company's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Stephen Van Deventer"
Chairman, CEO and President


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the Supreme Court action. Often, but not always, forward-looking statements can be identified by words such as "plans", "expects", "may", "intends", "anticipates", "believes", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Forward looking statements are based on certain assumptions regarding the Company, including that the Supreme Court action will result in a judgement in favour of the Company against the BridgeMark Group and that the Company will be able to obtain the relief sought in the Notice of Civil Claim and the Company's research and development and business activities. Actual results could also differ from those projected in any forward-looking statements due to numerous factors including, risks and uncertainties relating to the Supreme Court action and the inability of the Company, to, among other things, enforce a judgment against the BridgeMark Group and to complete its research and product development programs as planned. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the healthcare and cannabis industries in Canada may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, intentions and assumptions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations intentions or assumptions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!
Thumb 8020 monitor 200 200  png

8020 Admin

5 months

8020 Admin posted a press release PreveCeutical Provides Year End Corporate Update in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - December 19, 2018) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical") is pleased to provide an update on the Company's progress in its ongoing corporate initiatives.


PreveCeutical has achieved several notable milestones this year and continues to execute its strategy to become a global preventive healthcare company. These milestones include: signing a letter of intent with Crushedit LLC ("Crushedit") in respect of a $16.25 million cannabidiol ("CBD") isolate supply agreement; entering into a natural health product licensing agreement (the "Licensing Agreement") with Asterion Cannabis Inc. ("Asterion"); launching a medicinal cannabis division (the "Cannabis Division"); completing a $6.5 million financing; and expanded its Australian operations.


The Company has reached its 2018 research targets for its scorpion venom-derived peptide program (the "Peptide Program") and the soluble gel ("Sol-gel") drug delivery platform program (the "Sol-gel Program") and completed a workshop in Australia to advance its dual gene therapy research and development program (the "Dual Gene Therapy Program").


Letters of Intent


In November, the Company announced that it had entered into a letter of intent (the "Crushedit LOI") with Crushedit, whereby PreveCeutical's Cannabis Division would supply Crushedit with a minimum of 2,500 kilograms of CBD isolate over a 12-month period at a purchase price of CAD $6,500.00 per kilogram, for aggregate proceeds of at least CAD $16,250,000.


The Company also announces that its letter of intent with the Penta 5 Group (see news release dated October 3, 2018) has expired. During its due diligence of the Penta 5 Group, the Company became aware of unexpected complexities regarding the structure of the group that made the proposed share purchase transaction unfeasible. The Company and the Penta 5 Group are in negotiations regarding possible alternative transaction structures involving the purchase or joint ventures of individual products. The Company continues to seek other revenue streams.


Licensing Agreement with Asterion


On August 14, 2018, Asterion granted PreveCeutical a worldwide licence to use, manufacture, distribute and sell three Health Canada approved natural health products (the "Natural Health Products"). The Natural Health Products consist of three natural sleep aids - "Blissful Sleep", "Blissful Sleep Ex" and "Skullcap Serenity". The ingredients in these Natural Health Products have traditionally been used in herbal medicine to aid sleep and relieve anxiety and pain. All of the Natural Health Products have undergone thorough testing and meet or exceed the requirements of the European Pharmacopoeia and Health Canada. The Company plans to begin manufacturing the Natural Health Products and selling them in retail pharmacies, health-conscious stores as well as on the Company's website.


Cannabis Division


The Cannabis Division is responsible for bringing medicinal cannabis-based products (the "Medicinal Cannabis Products") developed by the Company to market and overseeing the Company's Sol-gel Program and its resultant formulations. Through the sale of the Medicinal Cannabis Products, the Company aims to help consumers address a number of ailments, including chronic pain, epilepsy, anxiety disorders and more. Moving forward, the Cannabis Division will seek out additional cannabis products and technologies for the Company to commercialise, ranging from transdermal patches and topical creams to capsules and novel methods of administering the medicinal cannabis.


Financing


On June 29, 2018, the Company closed a non-brokered private placement of 130,799,750 units (the "Units") at a price of $0.05 per Unit for gross proceeds of $6,539,988. The proceeds will be used to fund the Company's research and development programs and for general working capital purposes.


Australian Operations


Expanded Operations and Aurora Cannabis Inc. Shipments


The Company expanded its operations and incorporated an Australian subsidiary, PreveCeutical (Australia) Pty Ltd. The decision to expand its Australian operations was influenced by Australia's strong foundation of academic and clinical research, as well as the Australian research and development tax incentives.


The Company conducts its research and development programs in Australia, and after successfully applying for and receiving the necessary permits, PreveCeutical arranged for two deliveries of medicinal cannabis from Canada by Aurora to the Pharmacy Australia Centre of Excellence at the University of Queensland for use in the Sol-gel Program.


The Sol-Gel Program


By applying the Sol-gel technology to cannabis, the Company intends to develop therapies for relief from a range of symptoms, including pain, inflammation, anxiety, seizures and neurological disorders. The advantages of Sol-gels over conventional liquid nasal sprays include: longer therapeutic effects, reduced dosage requirements and reduced negative side effects, such as irritation.


This year the Sol-gel Program included the preparation of Sol-gel formulations containing fixed CBD:THC concentrations, which, when sprayed using the Company's custom applicator, will be able to safely and consistently deliver CBD:THC to the central nervous system in predefined ratios. This will enable the development of Medicinal Cannabis Products tailored for a broad range of ailments and diseases; optimising the conditions for extracting cannabinoids from the five cannabis strains provided by the Company's licensed producer (LP) partner, Aurora; and developing the Company's custom Sol-gel applicator.


In September and November, the Company optimised a proprietary extraction protocol, developed an optimised protocol to convert phytocannabinoids from all five of the Company's cannabis strains from their acid to neutral forms, and announced encouraging results from its Sol-gel applicator trials for achieving direct nose-to-brain delivery in an adult human nasal cast.


Traditional liquid nasal sprays are not retained in the nasal cavity for any appreciable time, and are only capable of generating random spray and deposition. In contrast, the Company's Sol-gel Applicator generates a precise spray profile that directs the Sol-gel formulation high into the upper nasal cavity where it remains following rapid gelation. This is an important development, as the region targeted by the Sol-gel is adjacent to the olfactory epithelium which serves as a direct passage for molecules into the brain.


Dual Gene Therapy Research Program


In October, PreveCeutical's research team at the University of Queensland, held a two-day intensive workshop (the "Workshop"), which brought together leading scientific teams from the QIMR Berghofer Medical Research Institute in Brisbane and Murdoch University in Perth (the "Teams") to collaborate on PreveCeutical's Dual Gene Therapy Program, which is intended to address the increasing prevalence of obesity and diabetes using smart siRNA and tissue targeted bio-responsive delivery systems.


The primary objectives of the Workshop were to share key data derived to-date from gene engineering, delivery system design and synthesis and their evaluation in cellular models of diabetes and obesity. The Teams assessed and resolved potential assay bottlenecks, paving the way for high throughput screening of smart siRNA candidate libraries, which is anticipated to expedite the Program's progress.


During the Workshop, the Teams created a 10 to 12 month plan aimed at successfully concluding the current phase of the Dual Gene Therapy Program by demonstrating proof-of-concept in the delivery of smart siRNAs and effective in-cell modulation of a key biomarker implicated in diabetes and obesity.


Once the current phase of the Dual Gene Therapy Program is complete, it will move to the final phase where the safety and efficacy of the primary smart siRNA-delivery system constructs will be evaluated in preclinical models of diabetes and obesity.


The Peptide Program


Phase 1 of the Peptide Program yielded promising results, as PreveCeutical's research team identified eight peptide candidates for the Company's future Nature Identical™ peptide therapeutics, which are intended to treat, regulate and prevent cancer progression.


Phase 2 of the Peptide Program is now underway, as the Company works to re-design the peptides, with the goal of enhancing their biostability, while maintaining their potency during screening against well-characterised and defined targets associated with brain cancer. In Phase 3, the Company will begin to screen the peptides in cell-based cancer models.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for type 2 diabetes and obesity; a Sol-gel drug delivery program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9® is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on the Company's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Stephen Van Deventer"
Chairman, CEO and President


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the ability of the Company to enter into a definitive supply agreement with Crushedit and to supply CBD isolate thereunder, manufacture and sell the Natural Health Products and to develop and bring its Medicinal Cannabis Products to market; the efficacy of the Company's products, generally, matters related to the Company's current and planned research and development programs, including, the Sol-Gel Program, the Dual Gene Therapy Program and the Peptide Program; the Company's use of the proceeds of the Financing; the Company's anticipated business plans; and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "plans", "expects", "may", "intends", "anticipates", "believes", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Forward looking statements are based on certain assumptions regarding the Company, including expected results from research and development activities and that the Company will be able to obtain the financing required to carry out its planned future activities, retain and attract qualified research personnel and obtain and/or maintain the necessary intellectual property rights it needs to carry out its future business activities. Actual results could also differ from those projected in any forward-looking statements due to numerous factors including, risks and uncertainties relating to, complexities and delays in connection with research and development activities and the actual results of research and development activities; and the inability of the Company to, among other things, manufacture the Natural Health Products and supply the CBD isolate, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialise therapeutic and diagnostic technologies, execute its proposed business plans, pursue business partnerships, complete its research and product development programs as planned and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the healthcare and cannabis industries in Canada may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, intentions and assumptions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations intentions or assumptions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!
Thumb 8020 monitor 200 200  png

8020 Admin

6 months

8020 Admin posted a press release PreveCeutical Converts Acidic Phytocannabinoids to Neutral Form and Doubles Contents of Fingerprinted Cannabis Extract Library in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - November 20, 2018) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), announces that it has developed an optimized protocol to convert phytocannabinoids extracted from the Company's five cannabis strains from their acid forms to their neutral forms (the "Neutralization Protocol").


Specifically, the Company's Neutralization Protocol has confirmed the comprehensive conversion of cannabidiolic acid (CBDA) and tetrahydrocannabinolic acid (THCA) to their neutral forms, canabidiol (CBD) and tetrahydrocannabinol (THC), respectively, without generating any detectable degradative products in the process. Further, the Neutralization Protocol has been verified via High-Performance Liquid Chromatography (HPLC) analysis using commercial cannabinoid standards.


The successful conversion of phytocannabinoids from their acid to neutral forms is an important development from a clinical perspective, as reports continue to emerge highlighting the benefits of using both acid and neutral forms of cannabinoids in treating a range of diseases and ailments.


As a result of the Neutralization Protocol, PreveCeutical has now doubled the number of extracts in its fingerprinted cannabis extract library by adding the five neutral form cannabinoid extracts to the five acid form cannabinoid extracts which were entered into the library earlier in 2018. For further information on the fingerprinted cannabis extract library (see news releases dated September 4, 2018, and November 5, 2018).


Next, the Company intends to pursue independent incorporation of both the acid and neutral form extracts into its soluble gel drug delivery program (the "Sol-gel Program") to generate a range of cannabinoid-based soluble gel formulations (each, a "CBD Sol-gel Formulation"), complemented by the Company's custom soluble gel applicator device (the "Sol-gel Applicator") for nose-to-brain drug delivery.


The Company's Chief Research Officer, Dr. Harendra Parekh stated, "Having optimized the conditions for comprehensive conversion of phytocannabinoids from acid to neutral forms opens the door to a wider product range for PreveCeutical, which is aimed at meeting the ever-increasing demands by physicians and patients alike, for chemically-validated, dose-standardized products."


The CBD Sol-gel Formulations, when used with the Company's Sol-gel Applicator, will facilitate prolonged delivery of cannabinoids to patients' central nervous systems. The Company's medicinal cannabis division expects to be able to offer a broad product range that can be tailored to specific medical conditions. For example, the Company is currently developing a CBD Sol-gel Formulation with a cannabinoid composition designed to treat patient anxiety (see news release dated August 8, 2018).


PreveCeutical's Sol-gel Applicator is currently in development. The Company's research partner, the University of Queensland, has received several prototypes for the Sol-gel Applicator from the Company's manufacturer, and has been assessing their performance in the Sol-gel Program.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilising organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the Sol-gel Program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9 is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on the Company's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Stephen Van Deventer"
Chairman, CEO and President


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the completion of the Sol-gel Program, the utilisation of the Neutralization Protocol, the development of the Sol-gel Formulations and the Sol-gel Applicator, the efficacy of the Company's products, matters related to the Company's current and planned research and development programs, including the Sol-gel Program, the Company's anticipated business plans and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "plans", "expects", "may", "intends", "anticipates", "believes", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Actual results could differ from those projected in any forward-looking statements due to numerous factors including, risks and uncertainties relating to the inability of the Company, to, among other things, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialise therapeutic and diagnostic technologies, execute its proposed business plans, pursue business partnerships, complete its research programs as planned and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the biotechnology, pharmaceutical or cannabis industry, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!
Thumb 8020 monitor 200 200  png

8020 Admin

6 months

8020 Admin posted a press release PreveCeutical Confirms Encouraging Results from Sol-gel Applicator Trials for Achieving Direct Nose-to-Brain Delivery in an Adult Human Nasal Cast in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - November 19, 2018) -  PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), is pleased to provide an update on the soluble gel ("Sol-gel") drug delivery research and development program (the "Sol-gel Program"), that involves testing and formulating an array of cannabis strains for the development and commercialisation of cannabinoid-based Sol-gels. The Sol-gels are administered using a custom applicator device (the "Sol-gel Applicator") for direct and sustained nose-to-brain drug delivery.


Achieving patient benefit from use of medicinal cannabis for the management of central nervous system (the "CNS") conditions, such as epilepsy, anxiety and depression, is reliant upon achieving effective and sustained delivery of the cannabis-based therapeutic to brain tissue. When taken orally medicinal cannabis can cause gastrointestinal upset, and when absorbed across the gut it is rapidly broken down by enzymes. As common drug delivery methods do not provide effective and sustained delivery to the brain, the delivery of cannabinoids to the CNS is a universal problem. PreveCeutical is pleased to announce that it expects to address this issue through its Sol-gel platform and Sol-gel Applicator device for direct nose-to-brain delivery of cannabis-based therapeutics.


Traditional liquid nasal sprays are not retained in the nasal cavity for any appreciable time, and are only capable of generating random spray and deposition profiles as depicted in Figure 1a and Figure 1b, respectively.


Cannot view this image? Visit: https://orders.newsfilecorp.com/files/5434/41134_prev1a.jpg

Figure 1a Liquid spray profile into adult human nasal cast from applicator device (no inhalation, cast temperature 34 °C).

To view an enhanced version of Figure 1a, please visit:
https://orders.newsfilecorp.com/files/5434/41134_prev1a_en.jpg


Cannot view this image? Visit: https://orders.newsfilecorp.com/files/5434/41134_prev1b.jpg

Figure 1b Liquid deposition profile into adult human nasal cast from applicator device (no inhalation, cast temperature 34 °C).

To view an enhanced version of Figure 1b, please visit:
https://orders.newsfilecorp.com/files/5434/41134_prev1b_en.jpg



In contrast, the Company's Sol-gel Applicator generates a precise spray profile that directs the Sol-gel formulation high into the upper nasal cavity (Figure 2a), where it remains following rapid gelation (Figure 2b). This is an important development, as the region targeted by the Sol-gel is adjacent to the olfactory epithelium (depicted by red arrows in the figures below), which serves as a direct passage for molecules into the brain.


 


Cannot view this image? Visit: https://orders.newsfilecorp.com/files/5434/41134_prev2a.jpg

Figure 2a Sol-gel spray profile into adult human nasal cast from applicator device (no inhalation, cast temperature 34 °C).

To view an enhanced version of Figure 2a, please visit:
https://orders.newsfilecorp.com/files/5434/41134_prev2a_en.jpg


 


Cannot view this image? Visit: https://orders.newsfilecorp.com/files/5434/41134_prev2b.jpg

Figure 2b Sol-gel deposition profile in adult human nasal cast from applicator device (no inhalation, cast temperature 34 °C).

To view an enhanced version of Figure 2b, please visit:
https://orders.newsfilecorp.com/files/5434/41134_prev2b_en.jpg


To exemplify the Sol-gel and Sol-gel Applicator's capabilities, an inhalation model was developed to mimic the inhalation action performed by patients when using nasal sprays, which combines an action of simultaneously spraying into a nostril accompanied by steady and deep nasal inhalation.


In the inhalation model, liquid sprays and Sol-gel sprays were compared for their delivery high into the nasal cavity along the target region, the olfactory epithelia. As shown in Figure 3a, the liquid spray profile shows random spray distribution with distinct large droplets, which is undesirable for the nose-to-brain delivery of therapeutics. In stark contrast, the Sol-gel formulation (Figure 3b) was drawn high into the nasal cavity, rapidly gelling and coating the target olfactory epithelium region. This encouraging development paves the way for the use of Sol-gels and the Sol-gel Applicator for direct nose-to-brain delivery.


 


Cannot view this image? Visit: https://orders.newsfilecorp.com/files/5434/41134_prev3a.jpg

Figure 3a Liquid spray generates a random droplet profile (inhalation model, cast temperature 34 °C).

To view an enhanced version of Figure 3a, please visit:
https://orders.newsfilecorp.com/files/5434/41134_prev3a_en.jpg


 


Cannot view this image? Visit: https://orders.newsfilecorp.com/files/5434/41134_prev3b.jpg

Figure 3b Sol-gel spray profile gels and coats olfactory epithelia (inhalation model, cast temperature 34 °C).

To view an enhanced version of Figure 3b, please visit:
https://orders.newsfilecorp.com/files/5434/41134_prev3b_en.jpg


The following video links showcase the contrasting spray profiles, in real-time, between a liquid and a Sol-gel being dispersed using the Sol-gel Applicator.


Video link to liquid spray profile demonstration
Video link to Sol-gel spray profile demonstration


The Company's Chief Research Officer, Dr. Harendra Parekh stated, "This is an important development for PreveCeutical, having demonstrated that its engineered Sol-gels and applicator device achieve delivery and retention directly at target tissue high in the nasal cavity, a feat that cannot be claimed by liquid sprays existing in the market currently. What's more exciting is that this outcome opens the door for PreveCeutical to potentially deliver a host of therapeutics from nose-to-brain in a reliable and sustained manner, which remains a significant challenge for many companies, globally."


The CBD Sol-gel formulations, when used with the Company's custom Sol-gel Applicator, will facilitate prolonged delivery of cannabinoids to patients' central nervous system. The Company's medicinal cannabis division expects to be able to offer a broad product range that can be tailored to specific medical conditions. For example, the Company is currently developing a CBD Sol-gel formulation with a cannabinoid composition designed to treat patient anxiety (see news release dated August 8, 2018).


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilising organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the Sol-gel Program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9 is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on the Company's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Stephen Van Deventer"
Chairman, CEO and President


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the completion of the Sol-gel Program, the development and testing of the Sol-gel formulations and the Sol-gel Applicator, the efficacy of the Company's products, matters related to the Company's current and planned research and development programs, including the Sol-gel Program, the Company's anticipated business plans and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "plans", "expects", "may", "intends", "anticipates", "believes", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Actual results could differ from those projected in any forward-looking statements due to numerous factors including, risks and uncertainties relating to the inability of the Company, to, among other things, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialise therapeutic and diagnostic technologies, execute its proposed business plans, pursue business partnerships, complete its research programs as planned and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the biotechnology, pharmaceutical or cannabis industries, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!
Thumb 8020 monitor 200 200  png

8020 Admin

6 months

8020 Admin posted a press release PreveCeutical Announces LOI with Crushedit LLC to Supply CBD Isolate for Expected Sale Proceeds of $16.25 Million in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - November 13, 2018) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H), (the "Company" or "PreveCeutical") announces that it has entered into a non-binding letter of intent dated November 9, 2018 (the "LOI") with Crushedit LLC ("Crushedit"), whereby PreveCeutical's newly created Cannabis Division (see news release dated July 24, 2018) will supply Crushedit with a minimum of 2,500 kilograms of Cannabidiol ("CBD") isolate over a 12 month period at a purchase price of CAD $6,500.00 per kilogram, for aggregate sale proceeds of at least CAD $16,250,000 (the "Transaction").


PreveCeutical's Chairman, Chief Executive Officer and President, Stephen Van Deventer commented, "We are extremely excited with this transaction for our Cannabis Division. The transaction is very beneficial to PreveCeutical as the revenue from the sales of the CBD isolate positions us for future growth to increase shareholder value and allows us to continue executing our vision of becoming a global preventive healthcare company."


Commercial Terms of the LOI


Under the terms of the LOI, PreveCeutical will supply Crushedit with a minimum of 2,500 kilograms of CBD isolate over a 12-month period. The funds paid by Crushedit in connection with the Transaction will be held in escrow until local testing of the CBD isolate is completed and all terms relating to the Transaction are agreed upon in a contract of sale to be entered into between the parties.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for type 2 diabetes and obesity; a Sol-gel drug delivery program; Nature IdenticalTM peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9® is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on PreveCeutical's website.


For more information about PreveCeutical, please visit www.preveceutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


For further information, please contact:


PREVECEUTICAL MEDICAL INC.
Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward- looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the entering into of a definitive contract of sale for the CBD isolate, completion of the Transaction (and the supply of 2,500 kilograms of CBD isolate), the future growth and revenue of the Company, the ability of the Company to develop and bring its cannabis-based products to market, the efficacy of the Company's products, matters related to the Company's current and planned research and development programs, including the Sol-gel program, the Company's anticipated business plans and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "plans", "expects", "may", "intends", "anticipates", "believes", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Forward looking statements are based on certain assumptions regarding the Company, including expected growth, results of operations, performance, industry trends and growth opportunities. Actual results could also differ from those projected in any forward-looking statements due to numerous factors including, risks and uncertainties relating to the inability of the Company, to, among other things, supply sufficient quantities of CBD isolate to Crushedit to meet the terms of the contract of sale, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialise therapeutic and diagnostic technologies, execute its proposed business plans, pursue business partnerships, complete its research programs as planned and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the healthcare and cannabis industries in Canada may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, intentions and assumptions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations intentions or assumptions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!
Thumb 8020 monitor 200 200  png

8020 Admin

7 months

8020 Admin posted a press release PreveCeutical Applies its Proprietary Extraction Protocol for Medical Cannabinoids to Two Additional Cannabis Strains in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - November 5, 2018) -  PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), announces that, in connection with its soluble gel drug delivery research and development program (the "Sol-gel Program"), it has now optimised the conditions for extracting cannabinoids from two additional cannabis strains provided by the Company's licensed producer (LP) partner, Aurora Cannabis Inc. ("Aurora").


The two strains possess discrete cannabinoid compositions that are consistent with Aurora's specifications, exemplifying the accuracy and precision of PreveCeutical's proprietary extraction protocol (the "Extraction Protocol") in quantifying cannabinoids present in plant extracts. For further information on the development of the Extraction Protocol, see the Company's news release dated September 4, 2018.


PreveCeutical's Chief Research Officer, Dr. Harendra Parekh stated, "This is an important verification of our efforts in reproducibly extracting and identifying cannabinoid and THC-rich fractions from plant material, leading to distinct fingerprints for a given strain. This development puts us in a good position for generating a standard operating procedure, encompassing the fingerprinted extracts in Sol-gel formulations."


PreveCeutical's Chairman, Chief Executive Officer and President, Stephen Van Deventer stated, "We are excited with how the fingerprinting of the cannabis strains is progressing. With the CBD Sol-gel formulations and applicator development on track, this brings us one step closer to getting the Sol-gel nose-to-brain delivery system to market."


PreveCeutical plans to fingerprint two more cannabis strains by 2019, which will bring the total number of distinct fingerprinted cannabis strains in the Company's target cannabinoid concentration range to five. The Company intends to use the fingerprints to generate a range of cannabinoid-based Sol-gel formulations (each, a "CBD Sol-gel Formulation"), each with a distinct, well-defined cannabinoid composition profile.


The CBD Sol-gel Formulations, when used with the Company's custom Sol-gel applicator (the "Sol-gel Applicator"), are expected to facilitate prolonged delivery of cannabinoids to patients' central nervous systems. The Company's medicinal cannabis division expects to be able to offer a broad product range that can be tailored to specific medical conditions. For example, PreveCeutical is currently developing a CBD Sol-gel Formulation with a cannabinoid composition designed to decrease patient anxiety (see news release dated August 8, 2018).


The Sol-gel Applicator is currently in development. The Company's research partner, The University of Queensland, has received several prototypes for the Sol-gel Applicator from the Company's manufacturer, and has been assessing their performance in the Sol-gel Program.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilising organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the Sol-gel Program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9 is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on the Company's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Stephen Van Deventer"
Chairman, CEO and President


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the completion of the Sol-gel Program, the utilisation of the Extraction Protocol, the development of the CBD Sol-gel Formulations and the Sol-gel Applicator, the efficacy of the Company's products, matters related to the Company's current and planned research and development programs, including the Sol-gel Program, the Company's anticipated business plans and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "plans", "expects", "may", "intends", "anticipates", "believes", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Actual results could differ from those projected in any forward-looking statements due to numerous factors including, risks and uncertainties relating to the inability of the Company, to, among other things, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialise therapeutic and diagnostic technologies, execute its proposed business plans, pursue business partnerships, complete its research programs as planned and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the biotechnology, pharmaceutical, or cannabis industry, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!
Thumb 8020 monitor 200 200  png

8020 Admin

7 months

8020 Admin posted a press release PreveCeutical Provides Update on Visit to Penta 5 Group's Facility for Due Diligence on Proposed Acquisition in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - October 31, 2018) -  PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), provides an update on its recent due diligence trip (the "Due Diligence Trip") to view a facility operated by the Penta 5 group of companies (the "Penta 5 Group") in connection with the Company's proposed acquisition (the "Acquisition") of the Penta 5 Group and its assets (see news release dated October 3, 2018).


The Due Diligence Trip to the 150,000 square foot facility located in Sarasota, Florida, included a tour of the facility's Food and Drug Administration approved filling and packing rooms, sealing machinery, bonded warehouse, as well as the full range of low and high-speed production lines and meetings with key members of the Penta 5 Group management and operations staff. PreveCeutical's management team reported that the facility exceeded their expectations, and that they are advancing to the next stage of the due diligence process.


Stephen Van Deventer, PreveCeutical's Chairman, Chief Executive Officer and President, stated, "We are pleased with the Penta 5 Group site visit and are moving forward with our due diligence using the data collected at the facility. We are encouraged by the scope of the Penta 5 Group facility's diverse capabilities and how the addition of their five divisions and contract ready products could be applied to the future growth of PreveCeutical."


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for type 2 diabetes and obesity; a Sol-gel drug delivery program; Nature IdenticalTM peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9® is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on PreveCeutical's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


For further information, please contact:


PREVECEUTICAL MEDICAL INC.
Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


 



Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include any statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the results of the Company's due diligence on the Penta 5 Group; the completion of the Acquisition; the ability of the Company to commercialize the Penta 5 Group's products; the manufacture and sale of the Company's current and future products; the efficacy of the Company's products, generally; matters related to the Company's current and planned research and development programs; the anticipated benefits of the Acquisition; the Company's anticipated business plans; and the prospect of its ability and success in executing its proposed plans. Forward-looking statements are based on certain assumptions regarding the Company, including expected growth, results of operations, performance, industry trends and growth opportunities. Actual results could differ from those projected in any forward-looking statements due to numerous factors including risks and uncertainties relating to the inability of the Company to, among other things, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations, including Canadian Securities Exchange acceptance of the Acquisition; complete the Acquisition; continue its research programs; and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the healthcare, cannabis, biotechnology, pharmaceutical or packaging industries, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!
Thumb 8020 monitor 200 200  png

8020 Admin

7 months

8020 Admin posted a press release PreveCeutical Holds Intensive Workshop to Advance Dual Gene Therapy Research Program for Type 2 Diabetes and Obesity in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - October 30, 2018) -  PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), is pleased to announce that its research team at the University of Queensland, recently held a two-day intensive workshop (the "Workshop"), which brought together leading scientific teams from the QIMR Berghofer Medical Research Institute in Brisbane and Murdoch University in Perth (the "Teams") to collaborate on PreveCeutical's dual gene therapy research and development program (the "Program"), which is intended to address the increasing prevalence of obesity and diabetes using smart siRNA and tissue targeted bio-responsive delivery systems.


The primary objectives of the Workshop were to share key data derived to-date from gene engineering, delivery system design and synthesis and their evaluation in cellular models of diabetes and obesity. The Teams assessed and resolved potential assay bottlenecks, paving the way for high throughput screening of smart siRNA candidate libraries, which is anticipated to expedite the Program's progress.


During the Workshop, the Teams created a 10 to 12 month plan aimed at successfully concluding the current phase of the Program by demonstrating proof-of-concept in the delivery of smart siRNAs and effective in-cell modulation of a key biomarker implicated in diabetes and obesity.


Once the current phase of the Program is complete, it will move to the final phase where the safety and efficacy of the primary smart siRNA-delivery system constructs will be evaluated in preclinical models of diabetes and obesity.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for type 2 diabetes and obesity; a Sol-gel drug delivery program; Nature Identical™ peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9® is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on the Company's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Stephen Van Deventer"
Chairman, CEO and President


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include any statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the ability of the Company to complete the current phase of the Program; matters related to the Company's current and planned research and development programs, including, the Program and the use of the Program's potential resultant products as therapies for diabetes or obesity; the efficacy of the Company's products, generally; the Company's anticipated business plans; and the prospect of its ability and success in executing its proposed plans. Forward-looking statements are based on certain assumptions regarding the Company, including expected growth, results of operations, performance, industry trends and growth opportunities. Actual results could differ from those projected in any forward-looking statements due to numerous factors including risks and uncertainties relating to the inability of the Company to, among other things, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations, including Canadian Securities Exchange acceptance of the Program; complete the Program; continue its research programs; and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the healthcare, biotechnology or pharmaceutical industries, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!
Thumb 8020 monitor 200 200  png

8020 Admin

7 months

8020 Admin posted a press release PreveCeutical to Visit Penta 5 Group's Packaging Facility for Due Diligence on Proposed Acquisition in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - October 15, 2018) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical") announces an update on the Company's due diligence on the Penta 5 group of companies (the "Penta 5 Group"), in connection with the proposed acquisition by the Company of the Penta 5 Group (the "Acquisition") and its assets, which include over seven brands, 40 market-ready products, previously announced on October 3, 2018.


To advance the due diligence process, the Company's management team has scheduled a due diligence trip (the "Due Diligence Trip") to the Penta 5 Group's leased 150,000 square foot state-of-the-art packaging facility (the "Facility") located in Sarasota, Florida, used for the packaging of food and beverages, non-food items and hemp products. The Due Diligence Trip will include a tour of the Facility's FDA approved filling and packing rooms, sealing machinery and bonded warehouse, as well as the full range of low and high-speed production lines.


Mr. Stephen Van Deventer, PreveCeutical's Chairman, CEO and President, stated, "We are happy with the results of our due diligence to date and are now ready to conduct an on-site inspection of the Penta 5 Group's operations. I am excited to understand the full scope of the Penta 5 facility's diverse capabilities and determine how it can be applied to the future growth of PreveCeutical."


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for type 2 diabetes and obesity; a Sol-gel drug delivery program; Nature IdenticalTM peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9® is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on PreveCeutical's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


For further information, please contact:


PREVECEUTICAL MEDICAL INC.
Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include any statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the results of the Company's due diligence on the Penta 5 Group; the completion of the Acquisition; the ability of the Company to commercialize the Penta 5 Group's products; the manufacture and sale of the Company's current and future products; the efficacy of the Company's products, generally; matters related to the Company's current and planned research and development programs; the anticipated benefits of the Acquisition; the Company's anticipated business plans; and the prospect of its ability and success in executing its proposed plans. Forward-looking statements are based on certain assumptions regarding the Company, including expected growth, results of operations, performance, industry trends and growth opportunities. Actual results could differ from those projected in any forward-looking statements due to numerous factors including risks and uncertainties relating to the inability of the Company to, among other things, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations, including Canadian Securities Exchange acceptance of the Acquisition; complete the Acquisition; continue its research programs; and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the healthcare, cannabis, biotechnology, pharmaceutical or packaging industries, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!

PreveCeutical Medical Inc.

lockPrivate Group

Headquartered in Vancouver, British Columbia, PreveCeutical Medical Inc. has a world class team with a passion for researching and developing innovative solutions for unmet clinical needs. Bringing to market treatments and therapies that make real, palpable differences in the lives of those who n...

people7 Members       (0)

Corporate Profile
Group Admins:
  • Thumb 8020 monitor 200 200  png
  • Thumb no photo
Request Membership


PreveCeutical Medical Inc.

lockPrivateGroup

Headquartered in Vancouver, British Columbia, PreveCeutical Medical Inc. has a world class team with a passion for re......

people7 Members       (0)

Thumb 8020 monitor 200 200  png

8020 Admin

13 hours

8020 Admin posted a press release PreveCeutical Granted Approval to Acquire and Use Human Mucosal Tissue for Final Phase of Sol-Gel Program in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - May 21, 2019) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), announces that the Company's research team at the University of Queensland has been granted the necessary approvals from a local hospital's Human Ethics Committee to acquire and use human nasal mucosal tissue (mucosal membrane) for the final phase of the cannabinoid-based, soluble gel ("Sol-gel") drug delivery research and development program (the "Sol-gel Program").


For this final phase of the Sol-gel Program, PreveCeutical intends to study and report on the delivery of the cannabis-infused Sol-gels to freshly explanted nasal mucosal tissue. PreveCeutical has previously demonstrated, using an adult human nasal cast, that the Company's cannabinoid-based Sol-gel is delivered to and retained directly at target tissue high in the nasal cavity when administered with a custom Sol-gel applicator device (the "Sol-gel Applicator") (see news release dated November 19, 2018).


PreveCeutical's President and Chief Science Officer, Dr. Mak Jawadekar stated, "Getting approval to acquire and use human mucosal tissue for this final phase of the Sol-Gel program allows us work on a proof of concept for Sol-Gel delivery in a laboratory setting."


PreveCeutical believes that the outcomes of its Sol-gel Program may be of value to companies interested in delivering cannabinoid/cannabis-based-derived pharmaceuticals to the central nervous system (the "CNS"). Achieving patient benefit from the use of medicinal cannabis for the management of CNS conditions, such as epilepsy, anxiety and depression, may be a function of achieving effective and sustained delivery of the cannabis-based therapeutic to brain tissue. When taken orally, medicinal cannabis can cause gastrointestinal upset, before being absorbed across the gut into the blood stream, where it is rapidly metabolised, and has the potential to interact with other medicines a patient may be taking. As common drug delivery methods do not provide effective and sustained delivery to the brain, the delivery of cannabinoids directly to the CNS remains a significant challenge.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilising organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the Sol-gel Program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Dr. Makarand (Mak) Jawadekar"
President& Chief Science Officer


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include any statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the ability of the Company to acquire human nasal mucosal tissue in quantities necessary to complete the final phase of the Sol-gel Program, and the Company's anticipated business plans and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "will", "pro forma", "plans", "expects", "may", "should", "budget", "schedules", "estimates", "forecasts", "intends", "anticipates", "believes", "potential", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Actual results could differ from those projected in any forward-looking statements due to numerous factors including risks and uncertainties relating to the risks associated with the completion of Sol-gel Program, actual results from tests using human nasal mucosal tissue and from clinical trials, dependence on collaborative partners and the prospects for negotiating additional corporate collaborations or licensing arrangements and their timing, the inability of the Company, to, among other things, protect its intellectual property, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialize any therapeutics from the Company's research programs, pursue business partnerships, complete its research programs as planned, and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the biotechnology or pharmaceutical industry, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.



To view the source version of this press release, please visit https://www.newsfilecorp.com/release/44909

!
Thumb 8020 monitor 200 200  png

8020 Admin

1 month

8020 Admin posted a press release PreveCeutical Partnership Leads to Two New Patent Filings in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - April 17, 2019) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical") announces that the Company's research collaboration with UniQuest and The University of Queensland ("UQ") has led to the filing of two new patent applications for cyclic peptides and their use in pain management (the "Patent Applications").


The Patent Applications follow from PreveCeutical entering into a research agreement in 2018 (see news release dated January 30, 2018) with UniQuest, UQ's commercialisation company. The research includes the application of UQ's disulphide linker technology to potentially develop non-addictive analgesics (the "Analgesics Research Program").


The two new Australian Patent Office patent files are:



  1. Australian Patent Application No. AU2019/900226, entitled "A Cyclic Peptide" filed January 24, 2019; and,

  2. Australian Patent Application No. AU2019/900292, entitled "A Cyclic Peptide" filed January 30, 2019.


PreveCeutical's President and Chief Science Officer, Dr. Mak Jawadekar stated: "I am pleased by the two new Australian patent applications which are based upon PreveCeutical's research collaboration with UQ and UniQuest. We are incredibly excited by our partnership with UniQuest and the intellectual property arising from the non-addictive analgesics program at UQ. The research program aims to develop a non-addictive alternative to opioid painkillers by developing cyclic peptides. Opioid-based pain treatments such as morphine, codeine and fentanyl activate the mu opioid receptor, which can be highly addictive. This research provides a potential mechanism for pain treatment without activating that receptor. An additional potential advantage of the cyclic peptides is their enhanced metabolic stability and more importantly oral bioavailability, meaning that they could be taken orally rather than intravenously."


UQ School of Pharmacy researchers, Associate Professor Peter Cabot and Dr. Harendra (Harry) Parekh are leading the two-year research program into the peptides and their potential application as a treatment for pain.


UniQuest CEO, Dr. Dean Moss stated: "The patent applications represent an important milestone in our relationship with PreveCeutical and follow the entry into three other research agreements with PreveCeutical in recent years, including an agreement to stabilise peptides isolated from scorpion venom for use in immune-boosting applications; an agreement for the development of a new formulation to deliver cannabinoids directly to the central nervous system via the nasal cavity; and an agreement for a gene therapy to treat diabetes and obesity."


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilising organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the soluble gel drug delivery research and development program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


About UniQuest


UniQuest is Australia's leading commercialisation entity, specialising in commercialising the intellectual property of The University of Queensland, a global top 50 university. UniQuest benchmarks in the top tier of technology transfer worldwide.


For more information about UniQuest, please visit https://uniquest.com.au/.


On Behalf of the Board of Directors of PreveCeutical


"Dr. Makarand (Mak) Jawadekar"
President & Chief Science Officer


For further information, please contact


PreveCeutical:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include any statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the granting of the Patent Applications and the continued research interests of PreveCeutical, PreveCeutical anticipated business plans and their prospects of success in executing their proposed plans. Often, but not always, forward-looking statements can be identified by words such as "will", "pro forma", "plans", "expects", "may", "should", "budget", "schedules", "estimates", "forecasts", "intends", "anticipates", "believes", "potential", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Forward looking statements are based on certain assumptions regarding PreveCeutical, including expected growth, results of operations, including PreveCeutical's research and development activities, performance, industry trends, growth opportunities, and that PreveCeutical will be able to obtain the financing required to carry out its planned future activities, retain and attract qualified research personnel and obtain and/or maintain the necessary intellectual property rights needed to carry out future business activities.


Actual results could differ from those projected in any forward-looking statements due to numerous factors including, risks and uncertainties relating to: complexities and delays in connection with research and development activities and the actual results of research and development activities including the Analgesics Research Program; the acceptance of the Patent Appplications and the granting of the patents thereunder; the ability of PreveCeutical, to, among other things, protect their respective intellectual property, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities; and the ability of PreveCeutical to commercialise the Analgesics Research Program, pursue business partnerships, complete their research programs as planned, and obtain the financing required to carry out their planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the biotechnology or pharmaceutical industry, may also adversely affect the future results or performance of PreveCeutical. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, PreveCeutical assume no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although PreveCeutical believe that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by PreveCeutical from time-to-time. These reports and PreveCeutical's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.


To view the source version of this press release, please visit https://www.newsfilecorp.com/release/44147

!
Thumb 8020 monitor 200 200  png

8020 Admin

1 month

8020 Admin posted a press release PreveCeutical Files Application to Human Ethics Committee to Acquire Human Tissue for the Final Phase of the Sol-Gel Program in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - April 15, 2019) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), announces the Company's research team at the University of Queensland has filed an application to a local hospital's Human Ethics Committee (the "Human Ethics Committee") to acquire human nasal mucosal tissue (mucosal membrane) for use in the final phase of the cannabinoid-based, soluble gel ("Sol-gel") drug delivery research and development program (the "Sol-gel Program").


PreveCeutical has previously demonstrated effective delivery and retention of the Sol-gels to the olfactory epithelium in an adult human nasal cast using a custom applicator device (the "Sol-gel Applicator") (see news release dated November 19, 2018).


PreveCeutical's President and Chief Science Officer, Dr. Mak Jawadekar stated: "This is an important next step for the Sol-gel Program. Having demonstrated, in an in-vitro model, using an adult human nasal cast, that the Company's CBD Sol-gel is delivered to and retained directly at target tissue high in the nasal cavity when administered with the Sol-gel Applicator, we look forward to testing the Sol-gels on human nasal tissue. This will allow PreveCeutical to potentially deliver a host of therapeutics safely from nose-to-brain in a reliable and sustained manner, which remains a significant challenge for many companies, globally."


PreveCeutical believes that the outcomes of its Sol-gel Program may be of value to companies interested in delivering pharmaceuticals to the central nervous system (the "CNS"). Achieving patient benefit from the use of medicinal cannabis for the management of CNS conditions, such as epilepsy, anxiety and depression, may be a function of achieving effective and sustained delivery of the cannabis-based therapeutic to brain tissue. When taken orally, medicinal cannabis can cause gastrointestinal upset, and when absorbed across the gut it is broken down by enzymes. As common drug delivery methods do not provide effective and sustained delivery to the brain, the delivery of cannabinoids to the CNS is a universal problem.


Should the application to the Human Ethics Committee be granted, the final phase of the Sol-gel Program may begin. During the final phase, the Company intends to study and report on the delivery of the cannabis-infused Sol-gels to freshly explanted nasal mucosal tissue.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilising organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the Sol-gel Program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Dr. Makarand (Mak) Jawadekar"
President& Chief Science Officer


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include any statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the ability of the Company to have its application to acquire human nasal mucosal tissue by the Human Ethics Committee approved, and if approved, to acquire human nasal mucosal tissue, and the Company's anticipated business plans and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "will", "pro forma", "plans", "expects", "may", "should", "budget", "schedules", "estimates", "forecasts", "intends", "anticipates", "believes", "potential", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Actual results could differ from those projected in any forward-looking statements due to numerous factors including risks and uncertainties relating to the risks associated with the completion of Sol-gel Program, actual results from clinical trials, dependence on collaborative partners and the prospects for negotiating additional corporate collaborations or licensing arrangements and their timing, the inability of the Company, to, among other things, protect its intellectual property, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialise any therapeutics from the Company's research programs, pursue business partnerships, complete its research programs as planned, and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the biotechnology or pharmaceutical industry, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.


To view the source version of this press release, please visit https://www.newsfilecorp.com/release/44078

!
Thumb 8020 monitor 200 200  png

8020 Admin

1 month

8020 Admin posted a press release PreveCeutical Announces Further Results from its Preliminary Screening of Peptides Derived from Blue Scorpion Venom in a Cell-Based Brain Cancer Model in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - April 10, 2019) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), is pleased to announce further positive results from the preliminary screening of key peptides from its scorpion venom-derived peptide research and development program (the "Peptide Program"), that is expected to enable the Company to generate Nature Identical™ peptide therapeutics intended for therapeutic applications. PreveCeutical's initial focus is to understand the activities of such peptides in cell-based brain cancer models.


Through preliminary screening in a glioblastoma (aggressive brain cancer) cell-based assay, PreveCeutical's research team has successfully identified four lead peptides that inhibit the activity of a target protein (the "Target Protein") implicit in the progression of certain glioblastomas (see news release dated March 11, 2019).


After further screening of the lead peptides in an invasion assay model, PreveCeutical is pleased to announce that the peptides' abilities to inhibit the activity of the Target Protein and the invasion potential by glioblastoma cell types has been confirmed. This is an important development given that "invasion" is a key driver of the aggressiveness, the poor prognosis and the rapid spread of glioblastoma.


Although this screening process is nearing completion, the Peptide Program is ongoing. This latest encouraging development has helped progress the Company towards assessing the efficacy of the lead peptides in more sophisticated neural oncosphere cell models of glioblastoma. The results from such additional screening will be helpful in determining further applications of research generated from the Peptide Program.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the soluble gel drug delivery program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Dr. Makarand Jawadekar"
President & Chief Science Officer


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include any statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the ability of the Company to generate Nature Identical™ peptide therapeutics for therapeutic applications, to develop a more detailed understanding of the activities of the peptides and assess the efficacy of the peptides in more sophisticated neural oncosphere cell models and the Company's anticipated business plans and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "will", "pro forma", "plans", "expects", "may", "should", "budget", "schedules", "estimates", "forecasts", "intends", "anticipates", "believes", "potential", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Actual results could differ from those projected in any forward-looking statements due to numerous factors including risks and uncertainties relating to the risks associated with the completion of Peptide Program, actual results from clinical trials, dependence on collaborative partners and the prospects for negotiating additional corporate collaborations or licensing arrangements and their timing, the inability of the Company, to, among other things, protect its intellectual property, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialise any therapeutics from the Company's research programs, pursue business partnerships, complete its research programs as planned, and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the biotechnology or pharmaceutical industry, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!
Thumb 8020 monitor 200 200  png

8020 Admin

2 months

8020 Admin posted a press release IIROC Trade Resumption - PREV in PreveCeutical Medical Inc.





Company:  PreveCeutical Medical Inc.


CSE Symbol: PREV (all issues)


Resumption (ET): 9:30 AM


IIROC can make a decision to impose a temporary suspension (halt) of trading in a security of a publicly-listed company. Trading halts are implemented to ensure a fair and orderly market. IIROC is the national self-regulatory organization which oversees all investment dealers and trading activity on debt and equity marketplaces in Canada.


SOURCE Investment Industry Regulatory Organization of Canada (IIROC)


View original content: http://www.newswire.ca/en/releases/archive/April2019/05/c8855.html

For further information about IIROC's trading halt policy, please see Trading Halts & Timely Disclosure (http://www.iiroc.ca/industry/marketmonitoringanalysis/Pages/Trading-Halts-Timely-Disclosure.aspx) at www.iiroc.ca under the Halts & Resumptions tab. Please note that IIROC staff cannot provide any information about a specific halt beyond what is contained in this halt notice. For general information about IIROC, contact IIROC's Complaints & Inquiries team at inquiries@iiroc.ca or 1-877-442-4322 (Option 2). For company-related enquiries, contact the company directly

!
Thumb 8020 monitor 200 200  png

8020 Admin

2 months

8020 Admin posted a press release Retraction to News Release dated April 4, 2019 in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - April 4, 2019) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), announces that, at the request of the Investment Industry Regulatory Organization of Canada, it hereby retracts certain statements regarding estimated annual production, valuation and harvest quantities from the Toowoomba Medicinal Cannabis Project contained in its news release dated April 4, 2019. The presentation of this information is not consistent with requirements for the disclosure of forward looking information.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the Sol-gel drug delivery program; Nature Identical™ peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


For further information, please contact:


PREVECEUTICAL MEDICAL INC.
Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


To view the source version of this press release, please visit https://www.newsfilecorp.com/release/43898

!
Thumb 8020 monitor 200 200  png

8020 Admin

2 months

8020 Admin posted a press release IIROC Trading Halt - PREV in PreveCeutical Medical Inc.


VANCOUVER, April 4, 2019 /CNW/ - The following issues have been halted by IIROC:


Company: PreveCeutical Medical Inc.


CSE Symbol: PREV (all Issues)


Reason: Pending Company Contact


Halt Time (ET): 15:07


IIROC can make a decision to impose a temporary suspension (halt) of trading in a security of a publicly-listed company. Trading halts are implemented to ensure a fair and orderly market. IIROC is the national self-regulatory organization which oversees all investment dealers and trading activity on debt and equity marketplaces in Canada.


SOURCE Investment Industry Regulatory Organization of Canada (IIROC) - Halts/Resumptions


View original content: http://www.newswire.ca/en/releases/archive/April2019/04/c2091.html



For further information about IIROC's trading halt policy, please see Trading Halts & Timely Disclosure (http://www.iiroc.ca/industry/marketmonitoringanalysis/Pages/Trading-Halts-Timely-Disclosure.aspx) at www.iiroc.ca under the Halts & Resumptions tab. Please note that IIROC staff cannot provide any information about a specific halt beyond what is contained in this halt notice. For general information about IIROC, contact IIROC's Complaints & Inquiries team at inquiries@iiroc.ca or 1-877-442-4322 (Option 2). For company-related enquiries, contact the company directly.Copyright CNW Group 2019

!
Thumb 8020 monitor 200 200  png

8020 Admin

2 months

8020 Admin posted a press release Asterion Welcomes Australian Government Awarding of Major Project Status for its Toowoomba Medicinal Cannabis Project in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - April 4, 2019) - Asterion Cannabis Inc. (P.ASTR) ("Asterion") and PreveCeutical Medical Inc. ("PreveCeutical") (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H), announce today that Asterion's wholly-owned Australian subsidiary, Asterion Australia Pty Ltd, has been awarded Major Project Status for Asterion's Toowoomba Medicinal Cannabis Project (the "Toowoomba Project" or the "Facility") by the Australia Federal Government.


Asterion's CEO, Stephen Van Deventer, welcomed the announcement by the Australian Federal Industry, Innovation and Science Minister, Hon Karen Andrews MP, and stated, "Asterion chose Australia to develop the world's largest medicinal cannabis glasshouse because of the Australian Government's ambition to become the world's largest exporter of cannabis products for medicinal purposes, as announced by the Australian Federal Health Minister Hon Greg Hunt MP in January 2018." Mr. Van Deventer continued, "Asterion looks forward to working with the Federal and Queensland Governments and the Toowoomba Council throughout the development process, to deliver the largest and most technically advanced glasshouse in the world to the south eastern Queensland community and to deliver the finest quality in medical cannabis products to patients."

 

Major Project Status recognises the strategic significance of the Toowoomba Project to Australia, and provides coordination and facilitation support as well as a single-entry point to a coordinated approvals process. In order for the Toowoomba Project to have been considered for Major Project Status, it had to meet the Major Project Status requirements, including an estimated investment of AUD $50 million or more, strategic significance to Australia and certain Australian government approvals. The project proponent must also have the financial resources to complete the approvals process and the project must have reasonable commercial viability.

 

Toowoomba Project

 

The Toowoomba Project will be located on 75 hectares in Toowoomba adjacent to the Wellcamp Airport. The Facility is expected to be built to European Union Good Manufacturing Practices for medicinal products (EU-GMP) standards and, when complete, is planned to include a 40 hectare (4.3 million square feet) state-of-the-art glasshouse for cultivation and processing, in addition to a research centre and manufacturing facility, including administration and staff facilities. The Toowoomba Project is expected to be among the largest glasshouse facilities globally. The Facility is also expected to have the most advanced glasshouse cultivation technologies, including AI and robotics, and set new benchmarks in productivity, control, product quality and consistency. The Facility is anticipated to employ a state of the art security systems and implement best practice procedures to ensure the physical security of production and shipping, as well as traceability of products after shipment.

 

A three-stage establishment plan for the Toowoomba Project is expected to be implemented commencing in the last quarter of 2019, with a total capital cost in the approximate amount of $450 million. A total daily direct workforce of an estimated 800 workers will be employed with an additional 300 part time and shift-based positions. These positions range from semi-skilled workers through to scientists undertaking advanced research in both medicines and horticulture.

 

It is estimated that annual production from the Facility will be approximately 500,000 kg of medicinal cannabis product, having an export value in excess of $1 billion, with approximately 20,000 plants harvested per day.

 

Research and Development

 

Clonal propagation research conducted at the Facility will be funded by Asterion and undertaken by Queensland University Queensland Alliance for Agriculture and Food Innovation (QAAFI) (www.qaafi.uq.edu.au), with the plan to develop an in vitro mass propagation protocol for selected cultivars of Asterion's elected cannabis strains.

 

Asterion is working with PreveCeutical and UniQuest Pty Limited on the development of new medical applications for cannabis in both preventative and treatment applications. In addition, under its September 26, 2018 development and joint venture agreement with Asterion, PreveCeutical will make available to Asterion its soluble gel (Sol-gel) delivery system (the "Sol-Gel System"). Sol-gels are taken via nasal administration and rapidly gel upon contact with mucosal tissue, which paves the way for direct nose-to-brain delivery. PreveCeutical is currently developing its Sol-Gel System, with the goal of developing the first, sustained-release, cannabis and CBD-based Sol-gel nose-to-brain delivery system that will provide relief across a range of indications from pain, inflammation, seizures, and neurological disorders.

 

About Asterion

 

Asterion is a Canadian cannabis company with operations in Australia, specializing in organic medical cannabis with a goal of becoming an industry leader in next generation cannabis products. The company is focused on the future of precision agriculture and aims to produce the highest quality genetically uniform cannabis strains, at an affordable price.

 

Asterion is led by a team of highly experienced executives with over 120 years of combined experience in medical cannabis, renewable energy, capital markets, and other highly relevant sectors across North America, Oceania, Europe, Africa and Asia.

 

About PreveCeutical

 

PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.

 

PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the Sol-gel drug delivery program; Nature Identical™ peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).

 

On Behalf of the Board of Directors of PreveCeutical

 

"Dr. Mak Jawadekar"

President and Chief Science Officer

 

On Behalf of the Board of Directors of Asterion

 

"Stephen Van Deventer"

Chief Executive Officer

 

For further information, please contact:

 

Preveceutical Medical Inc.

Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com

Asterion:

Investor Relations
info@asterioncannabis.com


 


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the construction of the Facility and the implementation date and capital costs in connection therewith, the development functionality, productivity, production capacity and features of the Facility and the efficacy, consistency and quality of the cannabis products produced at the Facility, including the products used in PreveCeuitcal's Sol-gel System, the outcome and success of the Toowoomba Project and the Sol-gel System, the workforce requirements to operate the Facility, matters related to Asterion and PreveCeutical's current and planned projects and programs, including the Toowoomba Project and the Sol-gel program, and Asterion and PreveCeutical's anticipated business plans and prospect of success in executing each of their plans. Often, but not always, forward-looking statements can be identified by words such as "will", "plans", "expects", "may", "intends", "anticipates", "believes", "proposes", "estimates" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Actual results could differ from those projected in any forward-looking statements due to numerous factors including, but not limited to, the inability of Asterion and PreveCeutical to, among other things, successfully carry out the Toowoomba Project and construct the Facility and obtain the required regulatory approvals and financing required for same, execute their proposed business plans and obtain the financing required to carry out planned future activities. Other factors such as general economic, market or business conditions, future prices of cannabis, changes in the financial markets and in the demand and market price for cannabis, or changes in laws, regulations and policies affecting the biotechnology or medical cannabis industry and delays in obtaining governmental and regulatory approvals, including for the Toowoomba Project and the Sol-gel program, may also adversely affect the future results or performance of Asterion and PreveCeutical. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, neither Asterion nor PreveCeutical assumes any obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although Asterion and PreveCeutical believe that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by Asterion and PreveCeutical from time-to-time.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.


To view the source version of this press release, please visit https://www.newsfilecorp.com/release/43892

!
Thumb 8020 monitor 200 200  png

8020 Admin

2 months

8020 Admin posted a press release PreveCeutical Announces Preliminary Screening Results of Peptides Derived From Blue Scorpion Venom in a Cell-Based Brain Cancer Model in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - March 11, 2019) -  PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), is pleased to announce positive results from the preliminary screening of key peptides from its scorpion venom-derived peptide research and development program (the "Peptide Program"), that is expected to enable the Company to generate Nature Identical™ peptide therapeutics intended for therapeutic applications. PreveCeutical's initial focus is to understand the activities of such peptides in cell-based brain cancer models.


Through preliminary screening in a glioblastoma cell-based assay, PreveCeutical's research team has successfully identified four lead peptides that inhibit the activity of a target protein implicit in the progression of certain aggressive brain cancers.


Further, the re-designed and synthesised peptides were found to be equally or more potent in the cell-based activity assay when compared to another scorpion peptide, Chlorotoxin. A series of more comprehensive screening assays are underway in the final stage of the Peptide Program, to allow the Company to develop a more detailed understanding of the activities of the peptides in progressively complex cell-based brain cancer models. No clinical studies have been planned to be undertaken at this time.


PreveCeutical's President, Dr. Mak Jawadekar, commented, "This is a key milestone for PreveCeutical, as this research program underway in Queensland, Australia has successfully identified four lead peptides from blue scorpion venom."


Dr. Harry Parekh, PreveCeutical's Chief Research Officer commented, "We have identified novel, lead peptide candidates that inhibit activity of a key protein implicated in driving the aggressive nature of certain brain cancers. From a practical perspective, these lead peptides are attractive as they are a fraction of the size and complexity of an earlier reported scorpion-derived peptide, Chlorotoxin."


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the soluble gel drug delivery program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9® is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on the Company's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Stephen Van Deventer"
Chairman and CEO


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include any statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the ability of the Company to generate Nature Identical™ peptide therapeutics for therapeutic applications, to develop a more detailed understanding of the activities of the peptides in complex cell-based brain cancer models and the Company's anticipated business plans and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "will", "pro forma", "plans", "expects", "may", "should", "budget", "schedules", "estimates", "forecasts", "intends", "anticipates", "believes", "potential", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Actual results could differ from those projected in any forward-looking statements due to numerous factors including risks and uncertainties relating to the inability of the Company, to, among other things, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialise any therapeutics from the Company's research programs, pursue business partnerships, complete its research programs as planned, and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the biotechnology or pharmaceutical industry, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.


To view the source version of this press release, please visit https://www.newsfilecorp.com/release/43322

!
Thumb 8020 monitor 200 200  png

8020 Admin

4 months

8020 Admin posted a press release PreveCeutical to Explore Partnerships with Pharmaceutical and Biotechnology Companies for the Co-Development of its Sol-Gel System in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - January 29, 2019) - PreveCeutical Medical Inc. (the "Company" or "PreveCeutical") (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H), announces that it plans to commence exploratory discussions with pharmaceutical and biotechnology companies developing therapies for neurological disorders, that are seeking a targeted nose-to-brain drug delivery system in connection with same, with the intention of forming a partnership for the co-development of the Company's soluble gel ("Sol-gel") system.


The Company has previously demonstrated effective delivery and retention of its Sol-gels to the olfactory epithelium in an adult human nasal cast using its custom applicator device (the "Sol-gel Applicator") (see news release dated November 19, 2018). PreveCeutical now believes that this system may be of value to companies interested in delivering pharmaceuticals to the central nervous system (CNS).


PreveCeutical believes that the pharmaceutical industry faces significant challenges in delivering drugs to the brain, and that this can be a major obstacle in successfully developing effective treatments for neurological disorders. Starting a dialogue with potential partners will assist PreveCeutical in gauging the potential value of its nose-to-brain delivery approach, and in assessing whether partnership opportunities exist.


PreveCeutical's Chief Science Officer, Dr. Mak Jawadekar, will be responsible for leading discussions with external partners for the co-development of this system. Dr. Jawadekar has 28 years of experience working at Pfizer Inc. For many of these years he was involved in external Drug Delivery Technology Assessment function involving novel applicable technologies, which are patent protected. Further, he has extensive experience in creating and cultivating external partnerships and alliances for such technologies. Dr. Jawadekar began his professional career at Pfizer Central Research in early 1982, after having completed his Ph.D. in Pharmaceutics at the University of Minnesota.


"Sol-gel technology has certainly shown significant promise in laboratory testing at this point. Eventually, I would like to see this proprietary technology be successfully applied to a drug which could be targeted for CNS delivery. At the right time, we would welcome an opportunity to work with a pharmaceutical or biotechnology company to co-develop the Sol-gel and Sol-gel Applicator to be used in pharmaceutical and therapeutic products," stated PreveCeutical's Chief Science Officer, Dr. Mak Jawadekar.


"I am quite excited about this initiative. PreveCeutical started to work on the Sol-gel program over 22 months ago. By now, achieving primary proof of concept (POC) goals are on target to be met and preliminary results observed to date seem to exceed our expectations. PreveCeutical looks forward to opening new doors to work on co-developing the Sol-gel platform. Under the direction of Dr. Jawadekar, I am extremely confident of the possibilities," said PreveCeutical's Chairman, CEO and President, Stephen Van Deventer.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilising organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the Sol-gel Program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9 is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on the Company's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Stephen Van Deventer"
Chairman, CEO and President


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the commencement of exploratory discussions, and the entry into of a partnership, with one or more pharmaceutical and biotechnology companies for the co-development of the Company's Sol-gel system, the development and testing of the Sol-gel formulations and the Sol-gel Applicator, the efficacy of the Company's products, matters related to the Company's current and planned research and development programs, including the Sol-gel drug delivery research and development program, the Company's anticipated business plans and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "plans", "expects", "may", "intends", "anticipates", "believes", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Actual results could differ from those projected in any forward-looking statements due to numerous factors including, risks and uncertainties relating to the inability of the Company, to, among other things, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialise therapeutic and diagnostic technologies, execute its proposed business plans, pursue business partnerships including, but not limited to, a partnership with a pharmaceutical and biotechnology company for the co-development of the Company's Sol-gel system, complete its research programs as planned and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the biotechnology, pharmaceutical or cannabis industries, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.



To view the source version of this press release, please visit https://www.newsfilecorp.com/release/42513

!
Thumb 8020 monitor 200 200  png

8020 Admin

4 months

8020 Admin posted a press release PreveCeutical Provides Update on Research Program for Development of Non-Addictive Analgesics in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - January 8, 2019) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical") is pleased to announce that it has recently completed a systematic and comprehensive series of in silico guided design, synthesis and potency screening of a library of carefully designed peptide constructs intended for development as non-addictive analgesics.


Through this meticulous process we have identified no less than five novel peptide constructs, which preferentially target the receptor subtype which is of interest to the Company and is purported to avoid addictive and tolerance-inducing side effects.


Furthermore, we confirm that this novel subset of peptides has demonstrated potency, in a well-accepted functional dose response assay, that is on par with clinically available agents, such as morphine.


PreveCeutical's peptide research program, led by the Company's Chief Research Officer, Dr. Harendra Parekh, is expected to further elaborate on this promising series of peptides, with the goal of employing design strategies that include a proprietary linker technology to enhance the analgesic peptides' stability, while maintaining their exceptional potency.


Dr. Parekh commented, "We are very pleased with this promising development, as a result of numerous iterations between our peptide design and cell-based screening efforts, we have now yielded a number of constructs which discriminate between the key pain receptors in the body, and importantly, avoid activation of those purported to lead to dependence."


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for type 2 diabetes and obesity; a soluble gel drug delivery program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9® is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on the Company's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Stephen Van Deventer"
Chairman, CEO and President


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, matters related to the Company's current and planned research and development programs, including the non-addictive analgesic peptides as a replacement to the highly addictive analgesics, such as morphine, the Company's anticipated business plans and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "plans", "expects", "may", "intends", "anticipates", "believes", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Forward looking statements are based on certain assumptions regarding the Company, including expected growth, results of operations, including the Company's research and development activities, performance, industry trends, growth opportunities, and that the Company will be able to obtain the financing required to carry out its planned future activities, retain and attract qualified research personnel and obtain and/or maintain the necessary intellectual property rights it needs to carry out its future business activities. Actual results could also differ from those projected in any forward-looking statements due to numerous factors including, risks and uncertainties relating to complexities and delays in connection with research and development activities and the actual results of research and development activities, and the inability of the Company, to, among other things, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialise therapeutic and diagnostic technologies, execute its proposed business plans, pursue business partnerships, complete its research and product development programs as planned and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the healthcare and cannabis industries in Canada may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, intentions and assumptions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations intentions or assumptions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!
Thumb 8020 monitor 200 200  png

8020 Admin

4 months

8020 Admin posted a press release PreveCeutical Files Notice of Civil Claim Against the BridgeMark Group in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - January 7, 2019) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), announces that on December 17, 2018 it filed a Notice of Civil Claim with the Supreme Court of British Columbia (the "Notice of Civil Claim") against Aly Babu Mawji, Justin Liu, BridgeMark Financial Corp., Rockshore Advisors Ltd. (formerly known as, Cam Paddock Enterprises Inc.), Detona Capital Corp., Escher Invest SA, Essos Corporate Services Inc., Jarman Capital Inc., JCN Capital Corp., Kendl Capital Limited, Lukor Capital, Northwest Marketing and Management Inc., Sway Capital Corp. and Tryton Financial Corp. (collectively, the "BridgeMark Group").


In the Notice of Civil Claim, PreveCeutical made claims against the BridgeMark Group for fraudulent misrepresentation, breach of contract, conspiracy, unjust enrichment and breach of duty of honest performance in connection with services that the BridgeMark Group failed to provide to PreveCeutical, and various consulting agreements (the "Consulting Agreements") and subscription agreements (the "Subscription Agreements") entered into between PreveCeutical and certain members of the BridgeMark Group


The relief sought by PreveCeutical in the Notice of Civil Claim includes: rescission of the Consulting Agreements and the Subscription Agreements; all necessary actions to effect such recession, including an order that the relevant members of the BridgeMark Group return the securities issued to them by PreveCeutical under the Subscription Agreements and refund the consulting fees paid to them by PreveCeutical under the Consulting Agreements; damages; costs; and pre and post judgement interest.


"Given the conduct of the BridgeMark Group, we have no other choice but to defend the interests of our shareholders by pursuing this Notice of Civil Claim," said PreveCeutical's Chairman, CEO and President, Stephen Van Deventer.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for type 2 diabetes and obesity; a soluble gel drug delivery program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9® is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on the Company's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Stephen Van Deventer"
Chairman, CEO and President


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the Supreme Court action. Often, but not always, forward-looking statements can be identified by words such as "plans", "expects", "may", "intends", "anticipates", "believes", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Forward looking statements are based on certain assumptions regarding the Company, including that the Supreme Court action will result in a judgement in favour of the Company against the BridgeMark Group and that the Company will be able to obtain the relief sought in the Notice of Civil Claim and the Company's research and development and business activities. Actual results could also differ from those projected in any forward-looking statements due to numerous factors including, risks and uncertainties relating to the Supreme Court action and the inability of the Company, to, among other things, enforce a judgment against the BridgeMark Group and to complete its research and product development programs as planned. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the healthcare and cannabis industries in Canada may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, intentions and assumptions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations intentions or assumptions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!
Thumb 8020 monitor 200 200  png

8020 Admin

5 months

8020 Admin posted a press release PreveCeutical Provides Year End Corporate Update in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - December 19, 2018) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical") is pleased to provide an update on the Company's progress in its ongoing corporate initiatives.


PreveCeutical has achieved several notable milestones this year and continues to execute its strategy to become a global preventive healthcare company. These milestones include: signing a letter of intent with Crushedit LLC ("Crushedit") in respect of a $16.25 million cannabidiol ("CBD") isolate supply agreement; entering into a natural health product licensing agreement (the "Licensing Agreement") with Asterion Cannabis Inc. ("Asterion"); launching a medicinal cannabis division (the "Cannabis Division"); completing a $6.5 million financing; and expanded its Australian operations.


The Company has reached its 2018 research targets for its scorpion venom-derived peptide program (the "Peptide Program") and the soluble gel ("Sol-gel") drug delivery platform program (the "Sol-gel Program") and completed a workshop in Australia to advance its dual gene therapy research and development program (the "Dual Gene Therapy Program").


Letters of Intent


In November, the Company announced that it had entered into a letter of intent (the "Crushedit LOI") with Crushedit, whereby PreveCeutical's Cannabis Division would supply Crushedit with a minimum of 2,500 kilograms of CBD isolate over a 12-month period at a purchase price of CAD $6,500.00 per kilogram, for aggregate proceeds of at least CAD $16,250,000.


The Company also announces that its letter of intent with the Penta 5 Group (see news release dated October 3, 2018) has expired. During its due diligence of the Penta 5 Group, the Company became aware of unexpected complexities regarding the structure of the group that made the proposed share purchase transaction unfeasible. The Company and the Penta 5 Group are in negotiations regarding possible alternative transaction structures involving the purchase or joint ventures of individual products. The Company continues to seek other revenue streams.


Licensing Agreement with Asterion


On August 14, 2018, Asterion granted PreveCeutical a worldwide licence to use, manufacture, distribute and sell three Health Canada approved natural health products (the "Natural Health Products"). The Natural Health Products consist of three natural sleep aids - "Blissful Sleep", "Blissful Sleep Ex" and "Skullcap Serenity". The ingredients in these Natural Health Products have traditionally been used in herbal medicine to aid sleep and relieve anxiety and pain. All of the Natural Health Products have undergone thorough testing and meet or exceed the requirements of the European Pharmacopoeia and Health Canada. The Company plans to begin manufacturing the Natural Health Products and selling them in retail pharmacies, health-conscious stores as well as on the Company's website.


Cannabis Division


The Cannabis Division is responsible for bringing medicinal cannabis-based products (the "Medicinal Cannabis Products") developed by the Company to market and overseeing the Company's Sol-gel Program and its resultant formulations. Through the sale of the Medicinal Cannabis Products, the Company aims to help consumers address a number of ailments, including chronic pain, epilepsy, anxiety disorders and more. Moving forward, the Cannabis Division will seek out additional cannabis products and technologies for the Company to commercialise, ranging from transdermal patches and topical creams to capsules and novel methods of administering the medicinal cannabis.


Financing


On June 29, 2018, the Company closed a non-brokered private placement of 130,799,750 units (the "Units") at a price of $0.05 per Unit for gross proceeds of $6,539,988. The proceeds will be used to fund the Company's research and development programs and for general working capital purposes.


Australian Operations


Expanded Operations and Aurora Cannabis Inc. Shipments


The Company expanded its operations and incorporated an Australian subsidiary, PreveCeutical (Australia) Pty Ltd. The decision to expand its Australian operations was influenced by Australia's strong foundation of academic and clinical research, as well as the Australian research and development tax incentives.


The Company conducts its research and development programs in Australia, and after successfully applying for and receiving the necessary permits, PreveCeutical arranged for two deliveries of medicinal cannabis from Canada by Aurora to the Pharmacy Australia Centre of Excellence at the University of Queensland for use in the Sol-gel Program.


The Sol-Gel Program


By applying the Sol-gel technology to cannabis, the Company intends to develop therapies for relief from a range of symptoms, including pain, inflammation, anxiety, seizures and neurological disorders. The advantages of Sol-gels over conventional liquid nasal sprays include: longer therapeutic effects, reduced dosage requirements and reduced negative side effects, such as irritation.


This year the Sol-gel Program included the preparation of Sol-gel formulations containing fixed CBD:THC concentrations, which, when sprayed using the Company's custom applicator, will be able to safely and consistently deliver CBD:THC to the central nervous system in predefined ratios. This will enable the development of Medicinal Cannabis Products tailored for a broad range of ailments and diseases; optimising the conditions for extracting cannabinoids from the five cannabis strains provided by the Company's licensed producer (LP) partner, Aurora; and developing the Company's custom Sol-gel applicator.


In September and November, the Company optimised a proprietary extraction protocol, developed an optimised protocol to convert phytocannabinoids from all five of the Company's cannabis strains from their acid to neutral forms, and announced encouraging results from its Sol-gel applicator trials for achieving direct nose-to-brain delivery in an adult human nasal cast.


Traditional liquid nasal sprays are not retained in the nasal cavity for any appreciable time, and are only capable of generating random spray and deposition. In contrast, the Company's Sol-gel Applicator generates a precise spray profile that directs the Sol-gel formulation high into the upper nasal cavity where it remains following rapid gelation. This is an important development, as the region targeted by the Sol-gel is adjacent to the olfactory epithelium which serves as a direct passage for molecules into the brain.


Dual Gene Therapy Research Program


In October, PreveCeutical's research team at the University of Queensland, held a two-day intensive workshop (the "Workshop"), which brought together leading scientific teams from the QIMR Berghofer Medical Research Institute in Brisbane and Murdoch University in Perth (the "Teams") to collaborate on PreveCeutical's Dual Gene Therapy Program, which is intended to address the increasing prevalence of obesity and diabetes using smart siRNA and tissue targeted bio-responsive delivery systems.


The primary objectives of the Workshop were to share key data derived to-date from gene engineering, delivery system design and synthesis and their evaluation in cellular models of diabetes and obesity. The Teams assessed and resolved potential assay bottlenecks, paving the way for high throughput screening of smart siRNA candidate libraries, which is anticipated to expedite the Program's progress.


During the Workshop, the Teams created a 10 to 12 month plan aimed at successfully concluding the current phase of the Dual Gene Therapy Program by demonstrating proof-of-concept in the delivery of smart siRNAs and effective in-cell modulation of a key biomarker implicated in diabetes and obesity.


Once the current phase of the Dual Gene Therapy Program is complete, it will move to the final phase where the safety and efficacy of the primary smart siRNA-delivery system constructs will be evaluated in preclinical models of diabetes and obesity.


The Peptide Program


Phase 1 of the Peptide Program yielded promising results, as PreveCeutical's research team identified eight peptide candidates for the Company's future Nature Identical™ peptide therapeutics, which are intended to treat, regulate and prevent cancer progression.


Phase 2 of the Peptide Program is now underway, as the Company works to re-design the peptides, with the goal of enhancing their biostability, while maintaining their potency during screening against well-characterised and defined targets associated with brain cancer. In Phase 3, the Company will begin to screen the peptides in cell-based cancer models.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for type 2 diabetes and obesity; a Sol-gel drug delivery program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9® is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on the Company's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Stephen Van Deventer"
Chairman, CEO and President


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the ability of the Company to enter into a definitive supply agreement with Crushedit and to supply CBD isolate thereunder, manufacture and sell the Natural Health Products and to develop and bring its Medicinal Cannabis Products to market; the efficacy of the Company's products, generally, matters related to the Company's current and planned research and development programs, including, the Sol-Gel Program, the Dual Gene Therapy Program and the Peptide Program; the Company's use of the proceeds of the Financing; the Company's anticipated business plans; and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "plans", "expects", "may", "intends", "anticipates", "believes", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Forward looking statements are based on certain assumptions regarding the Company, including expected results from research and development activities and that the Company will be able to obtain the financing required to carry out its planned future activities, retain and attract qualified research personnel and obtain and/or maintain the necessary intellectual property rights it needs to carry out its future business activities. Actual results could also differ from those projected in any forward-looking statements due to numerous factors including, risks and uncertainties relating to, complexities and delays in connection with research and development activities and the actual results of research and development activities; and the inability of the Company to, among other things, manufacture the Natural Health Products and supply the CBD isolate, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialise therapeutic and diagnostic technologies, execute its proposed business plans, pursue business partnerships, complete its research and product development programs as planned and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the healthcare and cannabis industries in Canada may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, intentions and assumptions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations intentions or assumptions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!
Thumb 8020 monitor 200 200  png

8020 Admin

6 months

8020 Admin posted a press release PreveCeutical Converts Acidic Phytocannabinoids to Neutral Form and Doubles Contents of Fingerprinted Cannabis Extract Library in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - November 20, 2018) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), announces that it has developed an optimized protocol to convert phytocannabinoids extracted from the Company's five cannabis strains from their acid forms to their neutral forms (the "Neutralization Protocol").


Specifically, the Company's Neutralization Protocol has confirmed the comprehensive conversion of cannabidiolic acid (CBDA) and tetrahydrocannabinolic acid (THCA) to their neutral forms, canabidiol (CBD) and tetrahydrocannabinol (THC), respectively, without generating any detectable degradative products in the process. Further, the Neutralization Protocol has been verified via High-Performance Liquid Chromatography (HPLC) analysis using commercial cannabinoid standards.


The successful conversion of phytocannabinoids from their acid to neutral forms is an important development from a clinical perspective, as reports continue to emerge highlighting the benefits of using both acid and neutral forms of cannabinoids in treating a range of diseases and ailments.


As a result of the Neutralization Protocol, PreveCeutical has now doubled the number of extracts in its fingerprinted cannabis extract library by adding the five neutral form cannabinoid extracts to the five acid form cannabinoid extracts which were entered into the library earlier in 2018. For further information on the fingerprinted cannabis extract library (see news releases dated September 4, 2018, and November 5, 2018).


Next, the Company intends to pursue independent incorporation of both the acid and neutral form extracts into its soluble gel drug delivery program (the "Sol-gel Program") to generate a range of cannabinoid-based soluble gel formulations (each, a "CBD Sol-gel Formulation"), complemented by the Company's custom soluble gel applicator device (the "Sol-gel Applicator") for nose-to-brain drug delivery.


The Company's Chief Research Officer, Dr. Harendra Parekh stated, "Having optimized the conditions for comprehensive conversion of phytocannabinoids from acid to neutral forms opens the door to a wider product range for PreveCeutical, which is aimed at meeting the ever-increasing demands by physicians and patients alike, for chemically-validated, dose-standardized products."


The CBD Sol-gel Formulations, when used with the Company's Sol-gel Applicator, will facilitate prolonged delivery of cannabinoids to patients' central nervous systems. The Company's medicinal cannabis division expects to be able to offer a broad product range that can be tailored to specific medical conditions. For example, the Company is currently developing a CBD Sol-gel Formulation with a cannabinoid composition designed to treat patient anxiety (see news release dated August 8, 2018).


PreveCeutical's Sol-gel Applicator is currently in development. The Company's research partner, the University of Queensland, has received several prototypes for the Sol-gel Applicator from the Company's manufacturer, and has been assessing their performance in the Sol-gel Program.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilising organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the Sol-gel Program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9 is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on the Company's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Stephen Van Deventer"
Chairman, CEO and President


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the completion of the Sol-gel Program, the utilisation of the Neutralization Protocol, the development of the Sol-gel Formulations and the Sol-gel Applicator, the efficacy of the Company's products, matters related to the Company's current and planned research and development programs, including the Sol-gel Program, the Company's anticipated business plans and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "plans", "expects", "may", "intends", "anticipates", "believes", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Actual results could differ from those projected in any forward-looking statements due to numerous factors including, risks and uncertainties relating to the inability of the Company, to, among other things, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialise therapeutic and diagnostic technologies, execute its proposed business plans, pursue business partnerships, complete its research programs as planned and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the biotechnology, pharmaceutical or cannabis industry, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!
Thumb 8020 monitor 200 200  png

8020 Admin

6 months

8020 Admin posted a press release PreveCeutical Confirms Encouraging Results from Sol-gel Applicator Trials for Achieving Direct Nose-to-Brain Delivery in an Adult Human Nasal Cast in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - November 19, 2018) -  PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), is pleased to provide an update on the soluble gel ("Sol-gel") drug delivery research and development program (the "Sol-gel Program"), that involves testing and formulating an array of cannabis strains for the development and commercialisation of cannabinoid-based Sol-gels. The Sol-gels are administered using a custom applicator device (the "Sol-gel Applicator") for direct and sustained nose-to-brain drug delivery.


Achieving patient benefit from use of medicinal cannabis for the management of central nervous system (the "CNS") conditions, such as epilepsy, anxiety and depression, is reliant upon achieving effective and sustained delivery of the cannabis-based therapeutic to brain tissue. When taken orally medicinal cannabis can cause gastrointestinal upset, and when absorbed across the gut it is rapidly broken down by enzymes. As common drug delivery methods do not provide effective and sustained delivery to the brain, the delivery of cannabinoids to the CNS is a universal problem. PreveCeutical is pleased to announce that it expects to address this issue through its Sol-gel platform and Sol-gel Applicator device for direct nose-to-brain delivery of cannabis-based therapeutics.


Traditional liquid nasal sprays are not retained in the nasal cavity for any appreciable time, and are only capable of generating random spray and deposition profiles as depicted in Figure 1a and Figure 1b, respectively.


Cannot view this image? Visit: https://orders.newsfilecorp.com/files/5434/41134_prev1a.jpg

Figure 1a Liquid spray profile into adult human nasal cast from applicator device (no inhalation, cast temperature 34 °C).

To view an enhanced version of Figure 1a, please visit:
https://orders.newsfilecorp.com/files/5434/41134_prev1a_en.jpg


Cannot view this image? Visit: https://orders.newsfilecorp.com/files/5434/41134_prev1b.jpg

Figure 1b Liquid deposition profile into adult human nasal cast from applicator device (no inhalation, cast temperature 34 °C).

To view an enhanced version of Figure 1b, please visit:
https://orders.newsfilecorp.com/files/5434/41134_prev1b_en.jpg



In contrast, the Company's Sol-gel Applicator generates a precise spray profile that directs the Sol-gel formulation high into the upper nasal cavity (Figure 2a), where it remains following rapid gelation (Figure 2b). This is an important development, as the region targeted by the Sol-gel is adjacent to the olfactory epithelium (depicted by red arrows in the figures below), which serves as a direct passage for molecules into the brain.


 


Cannot view this image? Visit: https://orders.newsfilecorp.com/files/5434/41134_prev2a.jpg

Figure 2a Sol-gel spray profile into adult human nasal cast from applicator device (no inhalation, cast temperature 34 °C).

To view an enhanced version of Figure 2a, please visit:
https://orders.newsfilecorp.com/files/5434/41134_prev2a_en.jpg


 


Cannot view this image? Visit: https://orders.newsfilecorp.com/files/5434/41134_prev2b.jpg

Figure 2b Sol-gel deposition profile in adult human nasal cast from applicator device (no inhalation, cast temperature 34 °C).

To view an enhanced version of Figure 2b, please visit:
https://orders.newsfilecorp.com/files/5434/41134_prev2b_en.jpg


To exemplify the Sol-gel and Sol-gel Applicator's capabilities, an inhalation model was developed to mimic the inhalation action performed by patients when using nasal sprays, which combines an action of simultaneously spraying into a nostril accompanied by steady and deep nasal inhalation.


In the inhalation model, liquid sprays and Sol-gel sprays were compared for their delivery high into the nasal cavity along the target region, the olfactory epithelia. As shown in Figure 3a, the liquid spray profile shows random spray distribution with distinct large droplets, which is undesirable for the nose-to-brain delivery of therapeutics. In stark contrast, the Sol-gel formulation (Figure 3b) was drawn high into the nasal cavity, rapidly gelling and coating the target olfactory epithelium region. This encouraging development paves the way for the use of Sol-gels and the Sol-gel Applicator for direct nose-to-brain delivery.


 


Cannot view this image? Visit: https://orders.newsfilecorp.com/files/5434/41134_prev3a.jpg

Figure 3a Liquid spray generates a random droplet profile (inhalation model, cast temperature 34 °C).

To view an enhanced version of Figure 3a, please visit:
https://orders.newsfilecorp.com/files/5434/41134_prev3a_en.jpg


 


Cannot view this image? Visit: https://orders.newsfilecorp.com/files/5434/41134_prev3b.jpg

Figure 3b Sol-gel spray profile gels and coats olfactory epithelia (inhalation model, cast temperature 34 °C).

To view an enhanced version of Figure 3b, please visit:
https://orders.newsfilecorp.com/files/5434/41134_prev3b_en.jpg


The following video links showcase the contrasting spray profiles, in real-time, between a liquid and a Sol-gel being dispersed using the Sol-gel Applicator.


Video link to liquid spray profile demonstration
Video link to Sol-gel spray profile demonstration


The Company's Chief Research Officer, Dr. Harendra Parekh stated, "This is an important development for PreveCeutical, having demonstrated that its engineered Sol-gels and applicator device achieve delivery and retention directly at target tissue high in the nasal cavity, a feat that cannot be claimed by liquid sprays existing in the market currently. What's more exciting is that this outcome opens the door for PreveCeutical to potentially deliver a host of therapeutics from nose-to-brain in a reliable and sustained manner, which remains a significant challenge for many companies, globally."


The CBD Sol-gel formulations, when used with the Company's custom Sol-gel Applicator, will facilitate prolonged delivery of cannabinoids to patients' central nervous system. The Company's medicinal cannabis division expects to be able to offer a broad product range that can be tailored to specific medical conditions. For example, the Company is currently developing a CBD Sol-gel formulation with a cannabinoid composition designed to treat patient anxiety (see news release dated August 8, 2018).


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilising organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the Sol-gel Program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9 is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on the Company's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Stephen Van Deventer"
Chairman, CEO and President


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the completion of the Sol-gel Program, the development and testing of the Sol-gel formulations and the Sol-gel Applicator, the efficacy of the Company's products, matters related to the Company's current and planned research and development programs, including the Sol-gel Program, the Company's anticipated business plans and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "plans", "expects", "may", "intends", "anticipates", "believes", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Actual results could differ from those projected in any forward-looking statements due to numerous factors including, risks and uncertainties relating to the inability of the Company, to, among other things, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialise therapeutic and diagnostic technologies, execute its proposed business plans, pursue business partnerships, complete its research programs as planned and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the biotechnology, pharmaceutical or cannabis industries, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!
Thumb 8020 monitor 200 200  png

8020 Admin

6 months

8020 Admin posted a press release PreveCeutical Announces LOI with Crushedit LLC to Supply CBD Isolate for Expected Sale Proceeds of $16.25 Million in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - November 13, 2018) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H), (the "Company" or "PreveCeutical") announces that it has entered into a non-binding letter of intent dated November 9, 2018 (the "LOI") with Crushedit LLC ("Crushedit"), whereby PreveCeutical's newly created Cannabis Division (see news release dated July 24, 2018) will supply Crushedit with a minimum of 2,500 kilograms of Cannabidiol ("CBD") isolate over a 12 month period at a purchase price of CAD $6,500.00 per kilogram, for aggregate sale proceeds of at least CAD $16,250,000 (the "Transaction").


PreveCeutical's Chairman, Chief Executive Officer and President, Stephen Van Deventer commented, "We are extremely excited with this transaction for our Cannabis Division. The transaction is very beneficial to PreveCeutical as the revenue from the sales of the CBD isolate positions us for future growth to increase shareholder value and allows us to continue executing our vision of becoming a global preventive healthcare company."


Commercial Terms of the LOI


Under the terms of the LOI, PreveCeutical will supply Crushedit with a minimum of 2,500 kilograms of CBD isolate over a 12-month period. The funds paid by Crushedit in connection with the Transaction will be held in escrow until local testing of the CBD isolate is completed and all terms relating to the Transaction are agreed upon in a contract of sale to be entered into between the parties.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for type 2 diabetes and obesity; a Sol-gel drug delivery program; Nature IdenticalTM peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9® is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on PreveCeutical's website.


For more information about PreveCeutical, please visit www.preveceutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


For further information, please contact:


PREVECEUTICAL MEDICAL INC.
Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward- looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the entering into of a definitive contract of sale for the CBD isolate, completion of the Transaction (and the supply of 2,500 kilograms of CBD isolate), the future growth and revenue of the Company, the ability of the Company to develop and bring its cannabis-based products to market, the efficacy of the Company's products, matters related to the Company's current and planned research and development programs, including the Sol-gel program, the Company's anticipated business plans and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "plans", "expects", "may", "intends", "anticipates", "believes", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Forward looking statements are based on certain assumptions regarding the Company, including expected growth, results of operations, performance, industry trends and growth opportunities. Actual results could also differ from those projected in any forward-looking statements due to numerous factors including, risks and uncertainties relating to the inability of the Company, to, among other things, supply sufficient quantities of CBD isolate to Crushedit to meet the terms of the contract of sale, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialise therapeutic and diagnostic technologies, execute its proposed business plans, pursue business partnerships, complete its research programs as planned and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the healthcare and cannabis industries in Canada may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, intentions and assumptions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations intentions or assumptions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!
Thumb 8020 monitor 200 200  png

8020 Admin

7 months

8020 Admin posted a press release PreveCeutical Applies its Proprietary Extraction Protocol for Medical Cannabinoids to Two Additional Cannabis Strains in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - November 5, 2018) -  PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), announces that, in connection with its soluble gel drug delivery research and development program (the "Sol-gel Program"), it has now optimised the conditions for extracting cannabinoids from two additional cannabis strains provided by the Company's licensed producer (LP) partner, Aurora Cannabis Inc. ("Aurora").


The two strains possess discrete cannabinoid compositions that are consistent with Aurora's specifications, exemplifying the accuracy and precision of PreveCeutical's proprietary extraction protocol (the "Extraction Protocol") in quantifying cannabinoids present in plant extracts. For further information on the development of the Extraction Protocol, see the Company's news release dated September 4, 2018.


PreveCeutical's Chief Research Officer, Dr. Harendra Parekh stated, "This is an important verification of our efforts in reproducibly extracting and identifying cannabinoid and THC-rich fractions from plant material, leading to distinct fingerprints for a given strain. This development puts us in a good position for generating a standard operating procedure, encompassing the fingerprinted extracts in Sol-gel formulations."


PreveCeutical's Chairman, Chief Executive Officer and President, Stephen Van Deventer stated, "We are excited with how the fingerprinting of the cannabis strains is progressing. With the CBD Sol-gel formulations and applicator development on track, this brings us one step closer to getting the Sol-gel nose-to-brain delivery system to market."


PreveCeutical plans to fingerprint two more cannabis strains by 2019, which will bring the total number of distinct fingerprinted cannabis strains in the Company's target cannabinoid concentration range to five. The Company intends to use the fingerprints to generate a range of cannabinoid-based Sol-gel formulations (each, a "CBD Sol-gel Formulation"), each with a distinct, well-defined cannabinoid composition profile.


The CBD Sol-gel Formulations, when used with the Company's custom Sol-gel applicator (the "Sol-gel Applicator"), are expected to facilitate prolonged delivery of cannabinoids to patients' central nervous systems. The Company's medicinal cannabis division expects to be able to offer a broad product range that can be tailored to specific medical conditions. For example, PreveCeutical is currently developing a CBD Sol-gel Formulation with a cannabinoid composition designed to decrease patient anxiety (see news release dated August 8, 2018).


The Sol-gel Applicator is currently in development. The Company's research partner, The University of Queensland, has received several prototypes for the Sol-gel Applicator from the Company's manufacturer, and has been assessing their performance in the Sol-gel Program.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilising organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for diabetes and obesity; the Sol-gel Program; Nature Identical peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9 is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on the Company's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Stephen Van Deventer"
Chairman, CEO and President


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the completion of the Sol-gel Program, the utilisation of the Extraction Protocol, the development of the CBD Sol-gel Formulations and the Sol-gel Applicator, the efficacy of the Company's products, matters related to the Company's current and planned research and development programs, including the Sol-gel Program, the Company's anticipated business plans and its prospect of success in executing its proposed plans. Often, but not always, forward-looking statements can be identified by words such as "plans", "expects", "may", "intends", "anticipates", "believes", "proposes" or variations of such words including negative variations thereof and phrases that refer to certain actions, events or results that may, could, would, might or will occur or be taken or achieved. Actual results could differ from those projected in any forward-looking statements due to numerous factors including, risks and uncertainties relating to the inability of the Company, to, among other things, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations required, including Canadian Securities Exchange acceptance of any planned future activities, commercialise therapeutic and diagnostic technologies, execute its proposed business plans, pursue business partnerships, complete its research programs as planned and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the biotechnology, pharmaceutical, or cannabis industry, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!
Thumb 8020 monitor 200 200  png

8020 Admin

7 months

8020 Admin posted a press release PreveCeutical Provides Update on Visit to Penta 5 Group's Facility for Due Diligence on Proposed Acquisition in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - October 31, 2018) -  PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), provides an update on its recent due diligence trip (the "Due Diligence Trip") to view a facility operated by the Penta 5 group of companies (the "Penta 5 Group") in connection with the Company's proposed acquisition (the "Acquisition") of the Penta 5 Group and its assets (see news release dated October 3, 2018).


The Due Diligence Trip to the 150,000 square foot facility located in Sarasota, Florida, included a tour of the facility's Food and Drug Administration approved filling and packing rooms, sealing machinery, bonded warehouse, as well as the full range of low and high-speed production lines and meetings with key members of the Penta 5 Group management and operations staff. PreveCeutical's management team reported that the facility exceeded their expectations, and that they are advancing to the next stage of the due diligence process.


Stephen Van Deventer, PreveCeutical's Chairman, Chief Executive Officer and President, stated, "We are pleased with the Penta 5 Group site visit and are moving forward with our due diligence using the data collected at the facility. We are encouraged by the scope of the Penta 5 Group facility's diverse capabilities and how the addition of their five divisions and contract ready products could be applied to the future growth of PreveCeutical."


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for type 2 diabetes and obesity; a Sol-gel drug delivery program; Nature IdenticalTM peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9® is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on PreveCeutical's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


For further information, please contact:


PREVECEUTICAL MEDICAL INC.
Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


 



Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include any statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the results of the Company's due diligence on the Penta 5 Group; the completion of the Acquisition; the ability of the Company to commercialize the Penta 5 Group's products; the manufacture and sale of the Company's current and future products; the efficacy of the Company's products, generally; matters related to the Company's current and planned research and development programs; the anticipated benefits of the Acquisition; the Company's anticipated business plans; and the prospect of its ability and success in executing its proposed plans. Forward-looking statements are based on certain assumptions regarding the Company, including expected growth, results of operations, performance, industry trends and growth opportunities. Actual results could differ from those projected in any forward-looking statements due to numerous factors including risks and uncertainties relating to the inability of the Company to, among other things, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations, including Canadian Securities Exchange acceptance of the Acquisition; complete the Acquisition; continue its research programs; and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the healthcare, cannabis, biotechnology, pharmaceutical or packaging industries, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!
Thumb 8020 monitor 200 200  png

8020 Admin

7 months

8020 Admin posted a press release PreveCeutical Holds Intensive Workshop to Advance Dual Gene Therapy Research Program for Type 2 Diabetes and Obesity in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - October 30, 2018) -  PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical"), is pleased to announce that its research team at the University of Queensland, recently held a two-day intensive workshop (the "Workshop"), which brought together leading scientific teams from the QIMR Berghofer Medical Research Institute in Brisbane and Murdoch University in Perth (the "Teams") to collaborate on PreveCeutical's dual gene therapy research and development program (the "Program"), which is intended to address the increasing prevalence of obesity and diabetes using smart siRNA and tissue targeted bio-responsive delivery systems.


The primary objectives of the Workshop were to share key data derived to-date from gene engineering, delivery system design and synthesis and their evaluation in cellular models of diabetes and obesity. The Teams assessed and resolved potential assay bottlenecks, paving the way for high throughput screening of smart siRNA candidate libraries, which is anticipated to expedite the Program's progress.


During the Workshop, the Teams created a 10 to 12 month plan aimed at successfully concluding the current phase of the Program by demonstrating proof-of-concept in the delivery of smart siRNAs and effective in-cell modulation of a key biomarker implicated in diabetes and obesity.


Once the current phase of the Program is complete, it will move to the final phase where the safety and efficacy of the primary smart siRNA-delivery system constructs will be evaluated in preclinical models of diabetes and obesity.


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for type 2 diabetes and obesity; a Sol-gel drug delivery program; Nature Identical™ peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9® is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on the Company's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


On Behalf of the Board of Directors


"Stephen Van Deventer"
Chairman, CEO and President


For further information, please contact:


Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include any statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the ability of the Company to complete the current phase of the Program; matters related to the Company's current and planned research and development programs, including, the Program and the use of the Program's potential resultant products as therapies for diabetes or obesity; the efficacy of the Company's products, generally; the Company's anticipated business plans; and the prospect of its ability and success in executing its proposed plans. Forward-looking statements are based on certain assumptions regarding the Company, including expected growth, results of operations, performance, industry trends and growth opportunities. Actual results could differ from those projected in any forward-looking statements due to numerous factors including risks and uncertainties relating to the inability of the Company to, among other things, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations, including Canadian Securities Exchange acceptance of the Program; complete the Program; continue its research programs; and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the healthcare, biotechnology or pharmaceutical industries, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!
Thumb 8020 monitor 200 200  png

8020 Admin

7 months

8020 Admin posted a press release PreveCeutical to Visit Penta 5 Group's Packaging Facility for Due Diligence on Proposed Acquisition in PreveCeutical Medical Inc.

Vancouver, British Columbia--(Newsfile Corp. - October 15, 2018) - PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) (the "Company" or "PreveCeutical") announces an update on the Company's due diligence on the Penta 5 group of companies (the "Penta 5 Group"), in connection with the proposed acquisition by the Company of the Penta 5 Group (the "Acquisition") and its assets, which include over seven brands, 40 market-ready products, previously announced on October 3, 2018.


To advance the due diligence process, the Company's management team has scheduled a due diligence trip (the "Due Diligence Trip") to the Penta 5 Group's leased 150,000 square foot state-of-the-art packaging facility (the "Facility") located in Sarasota, Florida, used for the packaging of food and beverages, non-food items and hemp products. The Due Diligence Trip will include a tour of the Facility's FDA approved filling and packing rooms, sealing machinery and bonded warehouse, as well as the full range of low and high-speed production lines.


Mr. Stephen Van Deventer, PreveCeutical's Chairman, CEO and President, stated, "We are happy with the results of our due diligence to date and are now ready to conduct an on-site inspection of the Penta 5 Group's operations. I am excited to understand the full scope of the Penta 5 facility's diverse capabilities and determine how it can be applied to the future growth of PreveCeutical."


About PreveCeutical


PreveCeutical is a health sciences company that develops innovative options for preventive and curative therapies utilizing organic and nature identical products.


PreveCeutical aims to be a leader in preventive health sciences and currently has five research and development programs, including: dual gene therapy for curative and prevention therapies for type 2 diabetes and obesity; a Sol-gel drug delivery program; Nature IdenticalTM peptides for treatment of various ailments; non-addictive analgesic peptides as a replacement to the highly addictive analgesics such as morphine, fentanyl and oxycodone; and a therapeutic product for treating athletes who suffer from concussions (mild traumatic brain injury).


PreveCeutical sells CELLB9®, an Immune System Booster. CELLB9® is an oral solution containing polarized and potentiated essential minerals extracted from a novel peptide obtained from Caribbean Blue Scorpion venom. This product is available on PreveCeutical's website.


For more information about PreveCeutical, please visit www.PreveCeutical.com, follow us on Twitter: http://twitter.com/PreveCeuticals and Facebook: www.facebook.com/PreveCeutical.


For further information, please contact:


PREVECEUTICAL MEDICAL INC.
Deanna Kress
Director of Corporate Communications & Investor Relations
+1-778-999-6063
deanna@PreveCeutical.com


Forward-Looking Statements:


This news release contains forward-looking statements and forward-looking information (collectively, "forward-looking statements") within the meaning of applicable Canadian and U.S. securities legislation, including the United States Private Securities Litigation Reform Act of 1995. All statements in this news release that are not purely historical are forward-looking statements and include any statements regarding beliefs, plans, expectations and orientations regarding the future including, without limitation, the results of the Company's due diligence on the Penta 5 Group; the completion of the Acquisition; the ability of the Company to commercialize the Penta 5 Group's products; the manufacture and sale of the Company's current and future products; the efficacy of the Company's products, generally; matters related to the Company's current and planned research and development programs; the anticipated benefits of the Acquisition; the Company's anticipated business plans; and the prospect of its ability and success in executing its proposed plans. Forward-looking statements are based on certain assumptions regarding the Company, including expected growth, results of operations, performance, industry trends and growth opportunities. Actual results could differ from those projected in any forward-looking statements due to numerous factors including risks and uncertainties relating to the inability of the Company to, among other things, obtain any required governmental, regulatory or stock exchange approvals, permits, consents or authorizations, including Canadian Securities Exchange acceptance of the Acquisition; complete the Acquisition; continue its research programs; and obtain the financing required to carry out its planned future activities. Other factors such as general economic, market or business conditions or changes in laws, regulations and policies affecting the healthcare, cannabis, biotechnology, pharmaceutical or packaging industries, may also adversely affect the future results or performance of the Company. These forward-looking statements are made as of the date of this news release and, unless required by applicable law, the Company assumes no obligation to update the forward-looking statements or to update the reasons why actual results could differ from those projected in these forward-looking statements. Although the Company believes that the statements, beliefs, plans, expectations, and intentions contained in this news release are reasonable, there can be no assurance that those statements, beliefs, plans, expectations, or intentions will prove to be accurate. Readers should consider all of the information set forth herein and should also refer to other periodic reports provided by the Company from time-to-time. These reports and the Company's filings are available at www.sedar.com.


Readers are cautioned that forward-looking statements are not guarantees of future performance or events and, accordingly, are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty of such statements.

!